TABLE 4-2 Differences in Mean Changes in Bone Mineral Content and Bone Mineral Density in Calcium Treated vs. Placebo Groups in Randomized, Controlled Trials in Adolescents

 

Group Mean Differences

Source

No.

Age (y)

Sex

Length Study (mo)

Calcium Intake Controls (mg/day)

Calcium Intake Treatment (mg/day)

Site

BMC (g)

Change in BMD (%)

Chan et al., 1995

48

9–13

female

12

728

1,437

Total body

35.52

 

Johnston et al., 1992

140

6–14

female and male

36

908

1,612

Midshaft radius

 

2.5

 

Distal radius

 

3.3

 

Lumbar spine

 

0.7

 

Femoral neck

 

0.4

 

Ward's triangle

 

1.2

 

Greater trochanter

 

1.8

Lloyd et al., 1993

94

11.9 ± 0.5

female

18

960

1,314

Total body

13.32

 


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