Calcium Retention Model (mg Ca/d) c

Clinical Trials d

No data

No data

Calcium intake of 800–900 gave retention of +174

Calcium intakes (mg/d) of 600 vs. 300 (Lee et al., 1995); 1,600 vs. 900 (Slemenda et al., 1997) resulted in greater increase in spinal BMC for higher intake groups.

M - 1,310

F - 1,070

Calcium intakes (mg/d) of: 1,314 vs. 960 (Lloyd et al., 1993) 1,437 vs. 728 (Chan et al., 1995) 1,612 vs. 908 (Johnston et al., 1992) resulted in a mean increase in BMC for all higher intake groups.

M - 1,236

F - 1,026

No data

M/F - 840–950

based on calcium balance

Calcium intakes (mg/d) of 1,572 vs. 810 resulted in reduced vertebral bone loss in premenopausal women (Baran et al., 1990).

M - 995

Calcium intake (mg/d) of > 1,200 resulted in no difference in bone loss in males.

F - 1200 e

as predicted from balance studies

Calcium intake (mg/d) of > 750, 800 and 1,000 showed less bone loss than lower intakes in females (see Table 4-1).

No data; e 1,200 mg extrapolated from data in 51–70 year olds

Calcium intake (mg/d) of 1,200 vs. 750 resulted in reduced fracture rate and lower bone loss measured by BMD at various sites (Chapuy et al., 1992; Dawson-Hughes et al., 1997).

d The major outcome evaluated from the clinical trials reviewed was change in BMD at various bone sites or fracture rate in the > 70 year age group.

e These estimates were not derived from statistical analysis of calcium intake and retention data to determine desirable calcium intakes due to limitations in the range of calcium intakes that had been studied.

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