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Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (1998)
Institute of Medicine (IOM)

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. "6 Niacin." Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, DC: The National Academies Press, 1998.

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DRI Dietary Reference Intakes: For Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline
Niacin EAR and RDA Summary, Ages 19 Years and Older

On the basis of the data in Table 6-1 and with a minor (approximately 10 percent) decrease for energy in women, the EAR is set at 12 mg/day of NEs for men and 11 mg/day of NEs for women.

EAR for Men

19–30 years

12 mg/day of niacin equivalents

 

31–50 years

12 mg/day of niacin equivalents

 

51–70 years

12 mg/day of niacin equivalents

 

> 70 years

12 mg/day of niacin equivalents

EAR for Women

19–30 years

11 mg/day of niacin equivalents

 

31–50 years

11 mg/day of niacin equivalents

 

51–70 years

11 mg/day of niacin equivalents

 

> 70 years

11 mg/day of niacin equivalents

The data in Table 6-1 also suggest a CV of the niacin requirement that is greater than 10 percent. The wide variation in the efficiency of converting tryptophan to niacin may contribute to the large apparent variation. Thus, a CV of 15 percent is used; the RDA is defined as equal to the EAR plus twice the CV to cover the needs of 97 to 98 percent of the individuals in the group (therefore, for niacin the RDA is 130 percent of the EAR).

RDA for Men

19–30 years

16 mg/day of niacin equivalents

 

31–50 years

16 mg/day of niacin equivalents

 

51–70 years

16 mg/day of niacin equivalents

 

> 70 years

16 mg/day of niacin equivalents

RDA for Women

19–30 years

14 mg/day of niacin equivalents

 

31–50 years

14 mg/day of niacin equivalents

 

51–70 years

14 mg/day of niacin equivalents

 

> 70 years

14 mg/day of niacin equivalents

Pregnancy

Method Used to Estimate the Average Requirement

There is no direct evidence that would suggest a change in the niacin requirement during pregnancy. To derive the EAR for pregnant women, it is estimated that the need for niacin increases by 3 mg/day of NEs to cover increased energy utilization and growth in

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135
Front Matter (R1-R24)
Summary (1-16)
1 Introduction to Dietary Reference Intakes (17-26)
2 The B Vitamins and Choline: Overview and Methods (27-40)
3 A Model for the Development of Tolerable Upper Intake Levels (41-57)
4 Thiamin (58-86)
5 Riboflavin (87-122)
6 Niacin (123-149)
7 Vitamin B6 (150-195)
8 Folate (196-305)
9 Vitamin B12 (306-356)
10 Pantothenic Acid (357-373)
11 Biotin (374-389)
12 Choline (390-422)
13 Uses of Dietary Reference Intakes (423-436)
14 A Research Agenda (437-442)
A Origin and Framework of the Development of Dietary Reference Intakes (443-447)
B Acknowledgments (448-450)
C Système International d'Unités (451-452)
D Search Strategies (453-455)
E Methodological Problems Associated with Laboratory Values and Food Composition Data for B Vitamins (456-459)
F Dietary Intake Data from the Boston Nutritional Status Survey, 1981–1984 (460-465)
G Dietary Intake Data from the Continuing Survey of Food Intakes by Individuals (CSFII), 1994–1995 (466-477)
H Dietary Intake Data from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994 (478-501)
I Daily Intakes of B Vitamins by Canadian Men and Women, 1990, 1993 (502-506)
J Options for Dealing with Uncertainties in Developing Tolerable Upper Intake Levels (507-511)
K Blood Concentrations of Folate and Vitamin B12 from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994 (512-519)
L Methylenetetrahydrofolate Reductase (520-522)
M Evidence from Animal Studies on the Etiology of Neural Tube Defects (523-526)
N Estimation of the Period Covered by Vitamin B12 Stores (527-530)
O Biographical Sketches (531-536)
P Glossary and Abbreviations (537-540)
Index (541-567)