tors in women receiving high-dose oral contraceptives (Rose, 1978; Shane and Contractor, 1975). Plasma PLP concentrations are decreased but the decrease is quite small. Normalization of the tryptophan load test in subjects receiving oral contraceptives requires very high levels of PN, up to 25 mg (Rose, 1978). This probably reflects hormonal stimulation of tryptophan catabolism rather than any deficiency of B6 per se. These studies were conducted when the
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"7 Vitamin B6."
Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline.
Washington, DC: The National Academies Press, 1998.
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