Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline

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Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (1998)
Institute of Medicine (IOM)

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. "9 Vitamin B12." Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, DC: The National Academies Press, 1998.

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DRI Dietary Reference Intakes: For Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline

TABLE 9-6 Other Studies of Subjects with Pernicious Anemia Considered in Setting the Estimated Average Requirement for Vitamin B₁₂ for Adults

Reference	Number of Subjects	Age Range (y)
Suggested IM^a requirement > 2.0 µg
Hansen and Weinfeld, 1962	14
Suggested IM requirement of 1.0–2.0 µg
Bastrup-Madsen et al., 1983	112	33–78
Lindenbaum et al., 1990	44	NA^c
Other Studies
Best et al., 1956	6	NA
Will et al., 1959	40	NA
Sullivan and Herbert, 1965	8	46–86
^a IM = intramuscular. ^b 1,000 µg × 0.15 retention/90 d. ^c NA = not available. ^d 1,000 µg × 0.15 retention/182 d.

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Front Matter (R1-R24)

1 Introduction to Dietary Reference Intakes (17-26)

2 The B Vitamins and Choline: Overview and Methods (27-40)

3 A Model for the Development of Tolerable Upper Intake Levels (41-57)

4 Thiamin (58-86)

5 Riboflavin (87-122)

6 Niacin (123-149)

7 Vitamin B6 (150-195)

8 Folate (196-305)

9 Vitamin B12 (306-356)

10 Pantothenic Acid (357-373)

11 Biotin (374-389)

12 Choline (390-422)

13 Uses of Dietary Reference Intakes (423-436)

14 A Research Agenda (437-442)

A Origin and Framework of the Development of Dietary Reference Intakes (443-447)

B Acknowledgments (448-450)

C Système International d'Unités (451-452)

D Search Strategies (453-455)

E Methodological Problems Associated with Laboratory Values and Food Composition Data for B Vitamins (456-459)

F Dietary Intake Data from the Boston Nutritional Status Survey, 1981–1984 (460-465)

G Dietary Intake Data from the Continuing Survey of Food Intakes by Individuals (CSFII), 1994–1995 (466-477)

H Dietary Intake Data from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994 (478-501)

I Daily Intakes of B Vitamins by Canadian Men and Women, 1990, 1993 (502-506)

J Options for Dealing with Uncertainties in Developing Tolerable Upper Intake Levels (507-511)

K Blood Concentrations of Folate and Vitamin B12 from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994 (512-519)

L Methylenetetrahydrofolate Reductase (520-522)

M Evidence from Animal Studies on the Etiology of Neural Tube Defects (523-526)

N Estimation of the Period Covered by Vitamin B12 Stores (527-530)

O Biographical Sketches (531-536)

P Glossary and Abbreviations (537-540)

Index (541-567)