The following HTML text is provided to enhance online
readability. Many aspects of typography translate only awkwardly to HTML.
Please use the page image
as the authoritative form to ensure accuracy.
DRI Dietary Reference Intakes: For Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline
Seven fulfilled at least one criterion for tissue B12 deficiency
1 µg/d of B12 p.o.
Serum B12 rose to 64 pmol/L (87 pg/mL), well below normal; gastritis may have decreased absorption of any B12 inadvertently present in the food
None
Half had serum B12 values < 74 pmol/L (100 pg/mL)
0.07–0.25 µg/d of B12
Judged inadequate
0.3–0.65 µg/d of B12
Hematological responses seen but serum B12 ≤ 74 pmol/L (100 pg/mL) in all
Interpretation complicated by transfusions and intramuscular injections
c SD = standard deviation.
d NA = not available.
Possible Ancillary Method: Maintenance of a Serum B12Concentration That Is Consistent with a Normal Circulating MMA Value
Several investigators have urged the use of the serum MMA concentration as the most sensitive indicator of B12 status (Lindenbaum et al., 1990; Moelby et al., 1990; Savage et al., 1994b; Stabler et al., 1996). This indicator could not be used as the criterion for setting
