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Folate

B12

Pantothenic Acid

Biotin

Choline

Detailed subsections, questions for research

Need for internal reference is stated and values given when available; questions for research.

Questions for research

Short subsection

Not necessary

Folate

B12

Pantothenic Acid

Biotin

Choline

Conflicting, variable quality

Conflicting, quality mootb

Conflicting

Lacking, being improved

Substantial, acceptable quality

No, see Gregory (1997), Martin et al. (1992), Pfeiffer et al. (1997), Tamura et al. (1997)c

No, tissue methods poorly developed

Insufficient comparisons to assess

Yes, but very limited experience

New methods give somewhat higher results for some foods

Old estimates were too high, early assay not specific

c Gregory JF 3rd. 1997. Bioavailability of folate. Eur J Clin Nutr 51: S54–S59; Martin DC, Francis J, Protetch J, Huff J. 1992. Time dependency of cognitive recovery with cobalamin replacement: Report of a pilot study. J Am Geriatr Soc 40:168–172; Pfeiffer CM, Rogers LM, Gregory JF 3rd. 1997. Determination of folate in cereal-grain food products using trienzyme extraction and combined affinity and reversed-phase liquid chromatography. J Agric Food Chem 45:407–413; Tamura T, Mizuno Y, Johnston KE, Jacob RA. 1997. Food folate assay with protease, α-amylase, and folate conjugase treatments. J Agric Food Chem 45:135–139.



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