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Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (1998)
Institute of Medicine (IOM)

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. "Index." Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, DC: The National Academies Press, 1998.

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DRI Dietary Reference Intakes: For Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline

Adults, 19 through 50 years

AIs, 21

derivation of DRIs for, 21, 32

EARs, 8–9

extrapolation of data to other age groups, 31–33, 66

supplement use, 272

Adults, 51 through 70 years

AIs, 21

ULs, 48–49

Adults, >70 years

cognitive function, 160, 268

EARs, 8–9

pernicious anemia in, 317, 332–333

supplement use, 18, 79, 81, 113, 182, 273, 346, 462–465

ULs, 48

Adverse effects, 2, 5–6

biotin, 384–385

choline, 390, 408–410, 411

defined, 41

evidence of, 50–51

folate, 273–277

interindividual variability in sensitivity, 48–49

niacin, 123, 138, 140–142

nutrient-nutrient interactions, 41, 49, 51, 273–274

pantothenic acid, 370

research recommendations, 15, 441–442

riboflavin, 87, 115–116

source of nutrient and, 47–48

thiamin, 58, 81–82

vitamin B6, 150, 182–183, 186

vitamin B12, 346

African Americans. See Blacks

Aging. See also Life-stage groups;

individual life stages

and energy metabolism, 75, 110

and metabolism of nutrients, 213–214, 228–229, 233

and nutrient requirements, 318–320

and nutrient toxicity, 48

and plasma homocysteine, 159, 203, 518–519

Alanine aminotransferase, 157, 390, 394, 395, 403

Albumin, 89, 152, 198

Alcohol consumption and alcoholism and folate, 204, 211, 240, 263, 266, 268, 276, 525

and niacin, 126, 144

and thiamin, 58, 60

and vitamin B6, 164

and vitamin B12, 347

Allergic sensitivity, 81–82

Alopecia, 377, 378

American Academy of Pediatrics, 30, 31

Amino acid metabolism, 58, 88, 150, 151, 161, 196, 197, 358.

See also individual amino acids

Aminopterin, 246

Anaphylaxis, 81

Anemia, 90, 153, 200, 201, 233, 234, 267, 329, 334.

See also Pernicious anemia

Anencephaly, 241, 243

Aneurin. See Thiamin

Animal studies

choline, 396, 397, 398, 399, 413–414

considerations in use of data from, 53

extrapolation of data from, 28, 43–44, 46, 52, 55, 56, 153

neural tube defects, 244, 245, 523–525

relevance of, 50, 51, 211

vitamin B12 deficiency, 274, 310, 346

Antibiotics, 94, 313, 320

Anticonvulsants, 212, 240, 246, 276, 380, 525

Anti-inflammatory drugs (nonsteroidal), 212

Apotyrosine decarboxylase assay, 156

Ariboflavinosis, 90, 111

Arnold Chiari malformation, 241

Asians, pernicious anemia, 317

Aspartate aminotransferase, 157

Aspirin, 212

Asthma, 187, 212

Atherosclerosis, 260

Athletes, 64, 97, 400

Atrophic gastritis, 200, 312, 317, 318, 320, 331, 337, 340, 341, 342, 527

Avidin, 375–376, 379, 380

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Front Matter (R1-R24)
Summary (1-16)
1 Introduction to Dietary Reference Intakes (17-26)
2 The B Vitamins and Choline: Overview and Methods (27-40)
3 A Model for the Development of Tolerable Upper Intake Levels (41-57)
4 Thiamin (58-86)
5 Riboflavin (87-122)
6 Niacin (123-149)
7 Vitamin B6 (150-195)
8 Folate (196-305)
9 Vitamin B12 (306-356)
10 Pantothenic Acid (357-373)
11 Biotin (374-389)
12 Choline (390-422)
13 Uses of Dietary Reference Intakes (423-436)
14 A Research Agenda (437-442)
A Origin and Framework of the Development of Dietary Reference Intakes (443-447)
B Acknowledgments (448-450)
C Système International d'Unités (451-452)
D Search Strategies (453-455)
E Methodological Problems Associated with Laboratory Values and Food Composition Data for B Vitamins (456-459)
F Dietary Intake Data from the Boston Nutritional Status Survey, 1981–1984 (460-465)
G Dietary Intake Data from the Continuing Survey of Food Intakes by Individuals (CSFII), 1994–1995 (466-477)
H Dietary Intake Data from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994 (478-501)
I Daily Intakes of B Vitamins by Canadian Men and Women, 1990, 1993 (502-506)
J Options for Dealing with Uncertainties in Developing Tolerable Upper Intake Levels (507-511)
K Blood Concentrations of Folate and Vitamin B12 from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994 (512-519)
L Methylenetetrahydrofolate Reductase (520-522)
M Evidence from Animal Studies on the Etiology of Neural Tube Defects (523-526)
N Estimation of the Period Covered by Vitamin B12 Stores (527-530)
O Biographical Sketches (531-536)
P Glossary and Abbreviations (537-540)
Index (541-567)