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Plate XIII: Pseudopterogorgia elisabethae, a Caribbean gorgonian is the source of potent anti-inflammatory compounds. Photo courtesy of William Fenical, Scripps Institution of Oceanography. Plate XIV: Two mutants of Green Fluorescent Protein (GFP), derived from a jellyfish, are filsed to HIV genes encoding a cytoplasmic protein (green) and a nuclear protein (blue). GFP can be linked to a variety of genes to monitor protein expression and subcellular localization (Stauber et al., 1998~. Plate XV: Photo of the sea urchin [ytichinus pict?vs spawning. The female is inverted on top of the beaker and the plentiful orange eggs drop to the bottom. A spawning male appears to the side of the beaker--the white foam on the top of the urchin contains the sperm. Plate XVI: Confocal microscope images taken at 5-second intervals of a fertilization- induced calcium wave in a Pisaster ochraceus starfish oocyte. The color spectrum indicates the relative concentration of calcium where blue-green represents low calcium and yellow-red represents high calcium. Photo provided courtesy of Stephen A. Stricker, Department of Biology, University of New Mexico.

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Plate VIII: Reverse colored (warmest is deepest blue; coldest is red) sea surface tempera- ture image that shows the strong shoreward intrusion of Gulf Stream water (darkest blue, 28 C) into the nearshore regions of the North Carolina coast. The Gulf Stream and meanders of Gulf Stream water serve a transport mechanism for Gymnodinium breve red tide cells onto the continental shelf in the U.S. South Atlantic Bight. Image from the NOAA-9 polar orbiting satellite (AVHRR-advanced very high resolution radiometer) on October 31, 1987; image provided by Tom Leming, National Marine Fisheries Service (NMFS), NSTL, MS.

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Plate IX: These maps depict the HAB outbreaks known before (top) and after (bottom) 1972. This is not meant to be an exhaustive compilation of all events, but rather an indi- cation of major or recurrent HAB episodes. Neurotoxic shellfish poisoning = NSP, para- lytic shellfish poisoning = PSP, and amnesic shellfish poisoning = ASP (Anderson, 1995~.

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Plate VIII: Reverse colored (warmest is deepest blue; coldest is red) sea surface tempera- ture image that shows the strong shoreward intrusion of Gulf Stream water (darkest blue, 28 C) into the nearshore regions of the North Carolina coast. The Gulf Stream and meanders of Gulf Stream water serve a transport mechanism for Gymnodinium breve red tide cells onto the continental shelf in the U.S. South Atlantic Bight. Image from the NOAA-9 polar orbiting satellite (AVHRR-advanced very high resolution radiometer) on October 31, 1987; image provided by Tom Leming, National Marine Fisheries Service (NMFS), NSTL, MS.

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Plate IX: These maps depict the HAB outbreaks known before (top) and after (bottom) 1972. This is not meant to be an exhaustive compilation of all events, but rather an indi- cation of major or recurrent HAB episodes. Neurotoxic shellfish poisoning = NSP, para- lytic shellfish poisoning = PSP, and amnesic shellfish poisoning = ASP (Anderson, 1995~.

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b Plate XIIa: The deep-water marine sponge, Discodermia dissolute, from which the com- pound discodermolide is obtained. This sponge was collected at a depth of approximately 500 feet. Photo courtesy of Harbor Branch Oceanographic Institution, Inc., C)1998. Plate XIIb: Untreated human cancer cells stained with fluorescently labeled anti-alpha- tubulin antibody. The individual, green hair-like structures are microtubules which form an organized meshwork or cellular skeleton (cytoskeleton) in cells. Microtubules also assist in the segregation of chromosomes during cell division. Photo courtesy of Harbor Branch Oceanographic Institution, Inc., C)1998. Plate XIIc: Human cancer cells treated with discodermolide. The microtubule network has become reorganized due to the activity of discodermolide. This results in the forma- tion of microtubule bundles, disruption of cell division, and death of the cancer cells. Photo courtesy of Harbor Branch Oceanographic Institution, Inc., (~)1998.

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Plate XIII: Pseudopterogorgia elisabethae, a Caribbean gorgonian, is the source of potent anti-inflammatory compounds. Photo courtesy of William Fenical, Scripps Institution of Oceanography.

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