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Addendum to Chapter 10

Table A10-1 Internal Cancer Data From Arsenic-exposure Studies Conducted In Taiwan Region Endemic To Blackfoot Disease



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Page 307 Addendum to Chapter 10 Table A10-1 Internal Cancer Data From Arsenic-exposure Studies Conducted In Taiwan Region Endemic To Blackfoot Disease

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Page 308 TABLE A10-1 Internal Cancer Data from Arsenic-Exposure Studies Conducted in Taiwan Region Endemic to Blackfoot Diseasea   No. of     Person-Years Bladder Liver Lung Village Wells Arsenic Concentration, ppm Median M F M F M F M F 3-H 1 0.010 0.010 4,159 4,043 1 6 3 1 3 5 2-1 1 0.011 0.011 3,529 3,194 0 0 0 0 0 1 0-G 5 0.010, 0.010, 0.030, 0.259, 0.770 0.030 5,388 4,861 3 2 3 3 4 5 3-5 1 0.032 0.032 7,851 7,033 3 3 5 2 6 2 3-N 1 0.032 0.032 2,689 2,392 4 3 1 1 3 1 4-7 1 0.042 0.042 10,629 10,227 0 0 4 0 0 0 6-A 1 0.045 0.045 7,716 6,820 0 0 1 1 0 0 0-J 2 0.020, 0.080 0.050 6,501 5,888 1 0 2 2 0 0 3-L 2 0.053, 0.058 0.056 6,238 5,094 3 4 3 0 5 7 4-D 1 0.060 0.060 10,107 9,227 1 2 1 1 1 2 3-P 1 0.065 0.065 6,574 5,927 0 0 3 0 2 5 6-C 1 0.073 0.073 12,767 11,937 0 1 2 0 2 0 4-8 1 0.080 0.080 11,307 10,332 1 0 3 1 2 2 0-0 1 0.100 0.100 6,895 6,392 0 0 2 2 3 1 O-E 5 0.010, 0.085, 0.110, 0.288, 0.686 0.110 5,753 5,310 6 3 3 1 4 5 0-I 7 0.020, 0.050, 0.110, 0.110, 0.190, 0.580, 0.590 0.110 4,249 3,833 0 2 1 3 3 2 4-N 2 0.073, 0.172 0.123 4,709 4,291 0 0 3 1 1 2 4-J 1 0.126 0.126 6,508 6,026 0 1 6 1 2 2 2-D 1 0.256 0.256 9,702 8,869 0 2 2 1 7 1 0-D 1 0.256 0.256 3,872 3,412 1 3 2 3 5 2 3-Q 6 0.148, 0.198, 0.242, 0.276, 0.291, 0.458 0.259 5,580 5,079 2 0 4 2 5 4 4-M 1 0.307 0.307 2,953 2,758 1 0 0 0 2 3 6-6 1 0.307 0.307 5,364 4,505 3 0 3 1 4 1 4-E 2 0.340, 0.360 0.350 3,942 3,586 0 0 1 0 0 1 4-L 2 0.310, 0.485 0.398 3,069 2,723 1 1 1 0 0 1

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Page 309   No. of     Person-Years Bladder Liver Lung Village Wells Arsenic Concentration, ppm Median M F M F M F M F 4-F 11 0.120, 0.170, 0.229,0.260, 0.260, 0.406,0.469, 0.485, 0.595, 0.779, 0.819 0.406 4,482 3,886 2 3 1 0 5 1 3-1 1 0.448 0.448 4,551 4,259 2 3 5 1 4 3 5-G 1 0.467 0.467 3,179 5,298 7 5 2 3 7 1 4-P 1 0.504 0.504 5,843 5,397 1 0 1 1 1 1 0-H 5 0.050, 0.394, 0.520, 0.610,1.752 0.520 4,390 4,313 3 2 4 0 4 5 4-1 47 0.020, 0.020, 0.030, 0.090, 0.100, 0.110, 0.120, 0.5200.120, 0.160, 0.190, 0.230, 0.240, 0.250, 0.270, 0.270, 0.290, 0.290, 0.350, 0.370, 0.410, 0.430, 0.450, 0.510, 0.520, 0.540, 0.560, 0.660, 0.700, 0.730, 0.740, 0.760, 0.760, 0.760, 0.780, 0.810, 0.810, 0.840, 0.840, 0.850, 0.850, 0.850, 0.870, 0.880, 0.900, 0.930, 0.940, 0.970 0.520 4,870 4,432 2 2 1 0 3 5 3-J 2 0.529, 0.529 0.529 8,454 8,689 4 8 3 1 6 5 3-S 2 0.480, 0.595 0.538 4,287 3,667 4 3 7 0 8 4 3-9 1 0.544 0.544 3,655 3,413 0 1 1 1 1 0 2-2 10 0.560, 0.580, 0.580, 0.590, 0.597, 0.600, 0.618, 0.620, 0.650, 0.704 0.599 9,059 7,977 2 2 9 5 8 5 4-G 2 0.620, 0.680 0.650 2,425 2,108 2 0 0 0 2 2 5-4 2 0.630, 0.735 0.683 3,155 2,983 1 1 2 1 5 2 2-M 2 0.435, 0.950 0.693 11,123 11,263 9 9 6 4 14 4 0-F 5 0.415, 0.660, 0.694, 0.720, 0.749 0.694 7,010 5,720 5 1 8 3 2 9 3-R 5 0.397, 0.440, 0.698, 0.750,1.010 0.698 4,310 3,576 3 6 3 2 6 7 3-M 4 0.221, 0.329, 1.105,1.411 0.717 5,815 4,877 0 1 2 0 0 0 2-N 3 0.560, 0.934, 0.960 0.934 8,341 8,342 7 10 8 2 4 4 aData from Wu et al. 1989; Chen et al. 1992.

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Page 310 References Chen, C.J., C.W. Chen, M.M. Wu, and T.L. Kuo. 1992. Cancer potential in liver, lung, bladder and kidney due to ingested inorganic arsenic in drinking water. Br. J. Cancer 66:888-892. Wu, M.M., T.L. Kuo, Y.H. Hwang, and C.J. Chen. 1989. Dose-response relation between arsenic concentration in well water and mortality from cancers and vascular diseases. Am. J. Epidemiol. 130:1123-1232.