Below are the first 10 and last 10 pages of uncorrected machine-read text (when available) of this chapter, followed by the top 30 algorithmically extracted key phrases from the chapter as a whole.
Intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text on the opening pages of each chapter. Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.
Do not use for reproduction, copying, pasting, or reading; exclusively for search engines.
OCR for page R11
Nitrate and Nitrite in Drinking Water CONTENTS EXECUTIVE SUMMARY 1 1 INTRODUCTION AND BACKGROUND 9 2 HAZARD IDENTIFICATION 13 Methemoglobinemia, 13 Cancer, 15 Reproductive and Developmental Toxicity, 23 Other Effects, 27 3 DOSE-RESPONSE ASSESSMENT 29 Methemoglobinemia, 29 Cancer, 31 Reproductive and Developmental Toxicity, 32 Other Effects, 33 4 EXPOSURE ASSESSMENT 35 Exposure from Food and Water, 35 Endogenous Synthesis, 37 Estimated Daily Intake, 37 Biologic Fate, 42 5 RISK CHARACTERIZATION 45 Cancer Risks, 46 Noncancer Risks, 48
OCR for page R12
Nitrate and Nitrite in Drinking Water APPENDIX A Physiologically Based Pharmacokinetic Model for Assessing the Risk of Cancer Associated with Nitrate Exposure 51 REFERENCES 53
OCR for page R13
Nitrate and Nitrite in Drinking Water Nitrate and Nitrite in Drinking Water
OCR for page R14
Nitrate and Nitrite in Drinking Water This page in the original is blank.