Below are the first 10 and last 10 pages of uncorrected machine-read text (when available) of this chapter, followed by the top 30 algorithmically extracted key phrases from the chapter as a whole.
Intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text on the opening pages of each chapter.
Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.
Do not use for reproduction, copying, pasting, or reading; exclusively for search engines.
OCR for page R17
CONTENTS
1. INTRODUCTION. . . . ears
2. CHOLINESTERASE REACTIVATORS . . . . . ee.~eeeee.~e 3
Background, 3
Review of Available Information on 2-PAM, P2S, TMB-4,and
To~ogonin, 9
Characterist ice
Biochemistry
Mechanisms of Action
Pharmacokinetice
Adverse Effects
Gastrointestinal Effects
Cardiovascular Ef fects
Neuropharmacology
Mutagenic, Reproductive, arid Carcinogenic Effects
Therapeutic Use
Delayed and Long-Term Effects
Ef fee ts on Vol unteere
Conclusions, 46
3.
PSYCHOCHEMICALS 47
Background, 47
Review of Available Information on Phencyclidine, 53
Chemistry
Absorp tion, Fate, and - Eliminat ion
Animal Toxicology
Neurochemistry
Pharmacology
Genetic and Reproductive Ef fects
Delayed and Long-Term Effects
Effects on Volunteers
Review of Available Informa~cior~ on Dibenzopyrans:
Dimethylheptylpyran and Related Compounds, 79
Chemistry
Absorption, Fate, and Elimination
Animal Toxicology
Mechanism of Action
Neuropharmaco' ogy
OCR for page R18
Mutagen city, Teratogellicity, and Carcillogenicity
Delayed and Long-Term Effects
Ef fec ts on Vo lunt eers
Conclusions, 98
4 . IRRITANTS AND VESI(=TS ~ ~ ~ ~ ~ ~ ~ e ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ e ~ a e ~ ~ ~ ~ ~ a ~ ~ ~ 101
Background ~ 101
Review of Available Information on Mustard Gas, 104
Characteristics
Toxicology
Industrial and Military Exposures
Medical Ef fects
World War I Casualt ies: Sequelae
Effects on Human Subjects Tested at Edgewood
Summary
Review of Available Information on o-Ch~orobenzylidene
Malononi~crile, ~ 35
Charac teri at ice
Biochemistry and Physiology
Toxicology (In Vitro and Animal Studies)
Toxicology ( Humans )
Use of CS in Northern-" Ireland
Long-Term Followup
Effects on Human Subjects Tested at Edgewood
Summary
Review of Available Information on Chloroacetophenone, 171
Introduction
Toxicology (In Vitro and Animal Studies)
Toxicology i n Human Studies
Tear-Gas Weapons
Sensitization in Humans
LoDg-term Effects
Effects on Human Subjects Tested at Edgewood
Discussion
Summary
Review of Available Information on Dibenz~b,f]~l,4Josazepine, 187
Characteristics
Cytotoxicity
Toxicity in Animals
Toxicity in Humans
Effects on Humors Subjects Tested at Edgewood
Summary
OCR for page R19
Review of Available Information on Diphenylaminochlorarsine, 203
Characteristics
Toxicity in Animals
Toxicity in Humans
Effects on Human Subjects Tested at Edgewood
Summary
Review of Available Information on Brombenzyl Cyanide, 213
Characteristics
Toxicity in Animals
Toxicity in Humans
Effects on Human Subjects Tested at Edgewood
Summary
Review of Availab' e Information on Chloropicrin, 221
Characteristics
Toxicity in Ahimals
Toxicity in Hans
Mutagenicity
Carcinogenicity
Effects on Human Subjects Tested at Edgewood
Discussion
Summary
Review of Available Information on Nonanoyl Morpholide, 231
Characteristics
Toxicity in Humans
Effects on Human Subjects Tested at Edgewood
Discussion
Review of Available Information on I-Methoxy-1,3,5-cycloheptatriene, 235
Characteristics
Toxicity in Animals
Toxicity in Humans
Mutagenicity
Effects on Human Subjects
Summary
Review of Available Information on Effects on Human Exposures
to 123 Irritant Chemicals at Edgewood: Two-Man Bests 248
Conclusions, 251
OCR for page R20
APPENDIX A. HISTORY OF DIE EDGEWOOD TESTING PROGRAM; COLOR
SCREENING AND SELECTION. . . e ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ e ~ ~ ~ ~ ~ ~ ~ @ ~ ~ ~ ~ ~ 254
APPENDIX B ~ DIGEST SPORT——OXIMES .... ~ ... ~ ~ ~ e ~ ~ ~ ~ ~ ~ ~ e ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ 263