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may be to wait for the development and reporting of this information to support identification of industrial chemical drinking water contaminants warranting more detailed assessment.
In addition, emissions and release data contained in the toxic release inventory can be analyzed to identify chemicals presenting potential concerns owing to releases into drinking water sources.
Conclusion
This paper describes major components of EPA's program to assess, test, and manage the risk of new and existing industrial chemicals under TSCA. The paper also explores possible approaches to sorting and screening these chemicals to identify possible candidates that present drinking water concerns.
More information about TSCA and other EPA activities and programs can be found on EPA's Internet home page on the World Wide Web at http://www.epa.gov.
References
Auer, C. M. and D. H. Gould. 1987. Carcinogenicity assessment and the role of structure activity relationship (SAP,) analysis under TSCA Section 5. Environment Carcinogen Research C5(I):29-71.
Auer, C. M., J. V. Nabholz, and K. P. Baetcke. 1990. Mode of action and the assessment of chemical hazards in the presence of limited data: Use of structure-activity relationships (SAR) under TSCA Section 5. Environmental Health Perspectives 87:183-197.
Auer, C. M., M. Zeeman, J. V. Nabholz and R. G. Clements. 1994. SAR—The U.S. regulatory perspective. SAR & QSAR Environmental Research 2(1-2): 29-38.
EPA. 1998b. Guidelines for Completing Initial Review Exposure Report for New Chemical Substances. Washington, D.C.: OPPT/EAB.
NRC (National Research Council). 1984. Toxicity Testing: Strategies to Determine Needs and Priorities. Washington, D.C.: National Academy Press.
OECD (Organization for Economic Cooperation and Development). 1994. EPA/EC Joint Project on the Evaluation of (Quantitative) Structure Activity Relationships. OECD Environment Monographs No. 88. Paris: OECD.
Zeeman, M., C. M. Auer, R. G. Clements, J. V. Nabholz, and R. S. Boethling. 1995. U.S. EPA regulatory perspectives on the use of QSAR for new and existing chemical evaluations. SAR and QSAR Environmental Research 3(3):179-201.