B Acronyms


ABC—

airway-breathing-circulation

ACEP—

American College of Emergency Physicians

ACTH—

adrenal corticotropin hormone

ADH—

anti-diuretic hormone

ADP—

adenosine diphosphate

AMP—

adenosine monophosphate

APACHE—

acute physiology and chronic health evaluation

APAF- 1—

apoptosis-activating factor 1

AP 1—

activator protein 1

ARDS—

acute respiratory distress syndrome

ATLS®

Advanced Trauma Life Support®

ATP—

adenosine triphosphate

ATPase—

adenosine triphosphatase


BTLS—

basic trauma life support


c-Fos

protein

c-Jun

protein

ced C.elegens

death gene

Ca2+

calcium

CD—

family of leukocyte adhesion molecules

cGMP—

cyclic guanosine monophosphate

CINC—

cytokine-induced chemoattractant

CNS—

central nervous system

CO2

carbon dioxide

CPP32—

caspase 3

CPR—

cardiopulmonary resuscitation

CRADD—

a novel human apoptotic adaptor molecule for caspase-2



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OCR for page 167
B Acronyms ABC— airway-breathing-circulation ACEP— American College of Emergency Physicians ACTH— adrenal corticotropin hormone ADH— anti-diuretic hormone ADP— adenosine diphosphate AMP— adenosine monophosphate APACHE— acute physiology and chronic health evaluation APAF- 1— apoptosis-activating factor 1 AP 1— activator protein 1 ARDS— acute respiratory distress syndrome ATLS®— Advanced Trauma Life Support® ATP— adenosine triphosphate ATPase— adenosine triphosphatase BTLS— basic trauma life support c-Fos— protein c-Jun— protein ced C.elegens— death gene Ca2+— calcium CD— family of leukocyte adhesion molecules cGMP— cyclic guanosine monophosphate CINC— cytokine-induced chemoattractant CNS— central nervous system CO2— carbon dioxide CPP32— caspase 3 CPR— cardiopulmonary resuscitation CRADD— a novel human apoptotic adaptor molecule for caspase-2

OCR for page 167
DCLHb— diaspirin cross-linked hemoglobin DFO— desferoxamine DHEA— dihydroepiandrosterone DIC— disseminated intravascular coagulation DNA— deoxyribonucleic acid DNase— dioxyribonuclease ECF— extracellular fluid eIF— eukaryotic initiation factor EKG— electrocardiogram EMS— emergency medical services eNOS— endothelial nitric oxide synthase EPR— electron paramagnetic resonance ER— endoplasmic reticulum FACS— flow cytometry FADD— Fas-associated death domain FDA— U.S. Food and Drug Administration Fe3+— iron FKBP12— FK-binding protein FLICE— alternate name for caspase-8 GCSF— granulocyte colony-stimulating factor GCN2— an eIF2α kinase GSSH— oxidized glutathione H2— hydrogen H2O— water HES— hydroxyethyl starch HIV— human immunodeficiency virus HRI— hemin regulated inhibitor HSD— hypertonic saline dextran HTLV— human T-cell leukemia virus ICAM-1— intracellular adhesion molecule 1 ICAM-2— intracellular adhesion molecule 2 ICU— intensive care unit IGF— insulin-like growth factor IL— interleukin iNOS— inducible NO synthase IOM— Institute of Medicine IP-3— inositol triphosphate IP-3R— inositol triphosphate receptors IRES— internal ribosome entry site IRR— insulin receptor-related receptor

OCR for page 167
IRS-1— insulin-receptor substrate-1 ISS—  injury severity score IV— intravenous K+— potassium K ATP potassium-adenosine triphosphate kDa— kilodalton kg— kilogram LD50— fifty percent lethal dose LMA— intubating laryngeal mask airway M— molar MEG— mercaptoethylguanidine meq— milliequivalents ml— milliliters mmHG— millimeters of mercury MODS— multiple-organ dysfunction syndrome MORT1— a human protein that binds to the death domain of FAS/APO1 and induces apoptosis. mosM— milliosmolar m7GTP— where GTP is guanosine triphosphate mRNA— messenger ribonucleic acid MTLS— military trauma life support mV— millivolts ρM— micromolar Na+— sodium NAD— nicotinamide adenine dinucleotide NADPH— reduced nicotinamide adeninedinucleotide phosphate NAS— National Academy of Sciences NEDD 2— alternate name for caspase-2 NFκB— nuclear factor κB NO— nitric oxide NOS2— inflammatory NO synthase NRC— National Research Council NVC18 O2— oxygen OH— hydroxide ion p53— p53 gene PARP— poly(ADP ribose)polymerase PARS— poly(ADP ribose)synthase

OCR for page 167
PHTLS— pre-hospital trauma life support PKA— protein kinase A PKR— protein kinase PNA— polynitroxyl human serum albumin PP— phosphatase RES— reticuloendothelial system RTS— revised trauma score RyR— ryanodine receptor ser-51— serine at position 51 SH— src homology SOD— superoxide dismutase STAT-3— signal transducer and activator of transcription TNF-α— tumor necrosis factor alpha TNFR— Tumor necrosis factor receptor tRNA— transfer ribonucleic acid TRISS— trauma injury severity score