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Suggested Citation:"C: Conference Agenda." Institute of Medicine. 1999. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Washington, DC: The National Academies Press. doi: 10.17226/9625.
×

C Conference Agenda

Conference on Resuscitation Fluid Design and Resuscitation Protocols for Combat Casualties

National Academy of Sciences Auditorium

2101 Constitution Avenue, N.W.

Washington, D.C.

Thursday, September 17, 1998

8:30 a.m.

WELCOMING REMARKS AND OVERVIEW OF THE CONFERENCE

 

Clyde J. Behney

Deputy Executive Officer

Institute of Medicine

 

Anna Johnson-Winegar, Ph.D.

Head, Human Systems Department

Office of Naval Research

 

David E. Longnecker, M.D.

Robert D. Dripps Professor and Chair

Department of Anesthesia

University of Pennsylvania Health System

Committee Chair

Suggested Citation:"C: Conference Agenda." Institute of Medicine. 1999. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Washington, DC: The National Academies Press. doi: 10.17226/9625.
×

9:00

PANEL 1: OVERVIEW OF FLUID RESUSCITATION

(15-minute presentations, each followed by 5 minutes of discussion)

 

Ronald F. Bellamy, M.D., Colonel, USA, Retired

Borden Institute, Walter Reed Army Institute of Research

Trauma Epidemiology of Combat Casualties

 

Howard Champion, M.D.

University of Maryland, Baltimore

Classical Shock Research vs. Resuscitation Needs

 

Uwe Kreimeier, M.D.

Department of Anesthesiology, University of Munich

Resuscitation Research in Europe

10:00

BREAK

10:20

PANEL 2: TREATMENT OF BATTLEFIELD TRAUMA

(15-minute presentations, each followed by 5 minutes of discussion)

 

Issues

 

Steven P. Bruttig, Ph.D.

Novel Technologies, Inc.

Issues in Trauma Treatment on the Battlefield

 

Frank Butler, Jr., M.D., Captain, USN

Naval Special Warfare Command Detachment Pensacola

Issues of Trauma Treatment for Special Forces

 

Geoffrey S. F. Ling, M.D., Ph.D.

Uniformed Services University of the Health Sciences

Neurological Aspects of Battlefield Trauma

 

Strategies

 

Michael M. Krausz, M.D.

RAMBAM Medical Center, Haifa, Israel

Resuscitation Strategies in the Israeli Army

 

George C. Kramer, Ph.D.

University of Texas, Galveston

Hypertonic Saline/Dextran Resuscitation: Novel Methods of Delivering Fluids on the Battlefield

Suggested Citation:"C: Conference Agenda." Institute of Medicine. 1999. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Washington, DC: The National Academies Press. doi: 10.17226/9625.
×

 

Monitoring

 

Frederick J. Pearce, Ph.D.

Walter Reed Army Institute of Research

Casualty Resuscitation and Monitoring Devices Under Development by the U.S. Army

12:20 p.m.

LUNCH

1:20

AGENDA ACCOMODATION I

(15-minute presentations, each followed by 5 minutes of discussion)

 

Jane Shelby, Ph.D.

University of Utah

Melatonin Therapy in Acute Trauma (from Panel 7)

 

Richard McCarron, M.D.

Naval Medical Research Institute

Hibernation as a Model for Tolerance to Ischemia (from Panel 8)

2:00

PANEL 3: ANIMAL MODELS OF HEMORHAGIC SHOCK

(15-minute presentations, each followed by 5 minutes of discussion)

 

Frederick J. Pearce, Ph.D.

Walter Reed Army Institute of Research

Animal Models of Hemorrhagic Shock and Physiological Responses to Hemorrhage

 

Kenneth G. Proctor, Ph.D.

University of Tennessee

Models of Combined Hemorrhage and Injury

 

Alfred Ayala, Ph.D.

Rhode Island Hospital

Effects of the Extent of Hypotension and Rates of Hemorrhage and Outcome in Animal Models

3:00

BREAK

3:20

PANEL 4: PATHOPHYSIOLOGY AND METABOLIC SEQUELAE

(15-minute presentations, each followed by 5 minutes of discussion)

Suggested Citation:"C: Conference Agenda." Institute of Medicine. 1999. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Washington, DC: The National Academies Press. doi: 10.17226/9625.
×

 

Richard Veech, M.D., D.Phil.

National Institute on Alcohol Abuse and Alcoholism

National Institutes of Health

Cellular Energetics and Fluid Design Issues

 

Ajay Verma, M.D., Ph.D., Major, USA

Uniformed Services University of the Health Sciences

Strategies for Supporting Energy Demand During Resuscitation

 

Edwin A. Deitch, M.D.

New Jersey Medical School

Sequelae of Hemorrhagic Shock (Intestinal Ischemia, Bacterial Translocation, ARDS)

 

Irshad H. Chaudry, Ph.D.

Rhode Island Hospital

Immune and Endocrine Aspects of Hemorrhage

 

Patricia E. Molina, M.D., Ph.D.

North Shore University Hospital

Cytokines in Hemorrhagic Shock

 

Timothy R. Billiar, M.D.

University of Pittsburgh

Role of Induced Nitric Oxide Synthase in Hemorrhagic Shock

5:20

CLOSING REMARKS

 

David E. Longnecker, M.D.

Committee Chair

5:45

ADJOURN

Suggested Citation:"C: Conference Agenda." Institute of Medicine. 1999. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Washington, DC: The National Academies Press. doi: 10.17226/9625.
×

National Academy of Sciences Auditorium

2101 Constitution Avenue, N.W.

Washington, D.C.

Friday, September 18, 1998

8:15 a.m.

OPENING REMARKS

 

David E. Longnecker, M.D.

Committee Chair

8:25

PANEL 5: COMPLICATIONS OF RESUSCITATION

(15-minute presentations, each followed by 5 minutes of discussion)

 

Richard Veech, M.D., D.Phil.

National Institutes of Health

(for Kieran Clarke, Ph.D., Oxford University)

Acute Toxicity of Lactate

 

C. Robert Valeri, M.D.

Boston University

Red Blood Cells and Platelets in Hemostasis

 

Peter Rhee, M.D.

Uniformed Services University of the Health Sciences

Stimulation of Inflammation by Standard Resuscitation Fluids

 

Y. John Wang, Ph.D.

Synzyme Tech., Inc., Irvine, Calif.

Polynitroxyl-Albumin for Treatment of Reperfusion Injury

 

Kenneth Mattox, M.D.

Baylor University

Complications of Fluid Resuscitation

10:05

BREAK

10:20

PANEL 6: NOVEL THERAPIES FOR HEMORRHAGE

(15-minute presentations, each followed by 5 minutes of discussion)

 

Alan S. Rudolph, Ph.D.

Naval Research Laboratory

Oxygen-Carrying Resuscitation Fluids

Suggested Citation:"C: Conference Agenda." Institute of Medicine. 1999. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Washington, DC: The National Academies Press. doi: 10.17226/9625.
×

 

Carleton J. C. Hsia, Ph.D.

Synzyme Tech., Inc., Irvine, Calif.

Reperfusion Injury in Hemorrhage as a Therapeutic Target

 

Paul Segall, Ph.D.

BioTime, Inc., Berkeley, Calif.

Using Hextend to Treat Hemorrhagic Shock

 

Bo E. Hedlund, Ph.D.

Biomedical Frontiers, Inc.

Beyond Volume Expansion: Treatment of Reperfusion Injury by Iron Chelation

 

John L. Gainer, Ph.D.

University of Virginia

Fluid Additive for Promoting Oxygen Consumption

 

T.M.S. Chang, M.D., Ph.D., M.R.C.P.

McGill University, Montreal, Canada

Polyhemoglobin-Superoxide Dismutase-Catalase: A New Blood Substitute

12:20 p.m.

LUNCH

1:20

AGENDA ACCOMODATION II

(15-minute presentations, each followed by 5 minutes of discussion)

 

William P. Wiesmann, M.D., Colonel, USA, Retired

Biostar

Occult Hemorrhage Detection on the Battlefield by Means of Novel Microwave Sensors/Detectors (from Panel 2)

 

John J. Lemasters, M.D., Ph.D.

University of North Carolina

Cellular Responses to Hypoxia (from Panel 4)

2:00

PANEL 7: NOVEL THERAPIES FOR HEMORRHAGE

(15-minute presentations, each followed by 5 minutes of discussion)

 

Andrew Salzman, M.D.

Cincinnati Children's Hospital

Treatment of Hemorrhage with MEG

Suggested Citation:"C: Conference Agenda." Institute of Medicine. 1999. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Washington, DC: The National Academies Press. doi: 10.17226/9625.
×

 

Alan Kim Johnson, Ph.D.

University of Iowa

Treatment of Hemorrhage with Melanocyte-Stimulating Hormones

 

William R. Millington, Ph.D.

University of Missouri, Kansas City

Neurobiology of Hemorrhagic Shock

 

Florence M. Rollwagen, Ph.D.

Uniformed Services University of the Health Sciences

Oral Cytokines for Treatment of Hemorrhagic Shock

 

Radha K. Maheshwari, Ph.D.

Uniformed Services University of the Health Sciences

Picroliv: Beneficial Effects in Hypoxia/Ischemia

 

Barbara A. Araneo, Ph.D.

Pharmadigm Biosciences Inc., Salt Lake City, Utah

Intravenous DHEA in the Treatment of Burn Syndrome

4:20

PANEL 8: HYPOTHERMIA IN TREATMENT OF HEMORRHAGE

(15-minute presentations, each followed by 5 minutes of discussion)

 

Samuel Tisherman, M.D.

University of Pittsburgh

Hypotensive Hypothermic Fluid Resuscitation During Uncontrolled Hemorrhagic Shock in Rats and Hypothermic Strategies for Suspended Animation with Delayed Resuscitation in Dogs

 

Peter Safar, M.D.

University of Pittsburgh

Pharmacologic-Hypothermic Suspended Animation

5:00

GENERAL DISCUSSION AND CLOSING REMARKS

 

David E. Longnecker, M.D.

Committee Chair

5:30

ADJOURN

Suggested Citation:"C: Conference Agenda." Institute of Medicine. 1999. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Washington, DC: The National Academies Press. doi: 10.17226/9625.
×
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Suggested Citation:"C: Conference Agenda." Institute of Medicine. 1999. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Washington, DC: The National Academies Press. doi: 10.17226/9625.
×
Page 171
Suggested Citation:"C: Conference Agenda." Institute of Medicine. 1999. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Washington, DC: The National Academies Press. doi: 10.17226/9625.
×
Page 172
Suggested Citation:"C: Conference Agenda." Institute of Medicine. 1999. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Washington, DC: The National Academies Press. doi: 10.17226/9625.
×
Page 173
Suggested Citation:"C: Conference Agenda." Institute of Medicine. 1999. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Washington, DC: The National Academies Press. doi: 10.17226/9625.
×
Page 174
Suggested Citation:"C: Conference Agenda." Institute of Medicine. 1999. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Washington, DC: The National Academies Press. doi: 10.17226/9625.
×
Page 175
Suggested Citation:"C: Conference Agenda." Institute of Medicine. 1999. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Washington, DC: The National Academies Press. doi: 10.17226/9625.
×
Page 176
Suggested Citation:"C: Conference Agenda." Institute of Medicine. 1999. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Washington, DC: The National Academies Press. doi: 10.17226/9625.
×
Page 177
Suggested Citation:"C: Conference Agenda." Institute of Medicine. 1999. Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries. Washington, DC: The National Academies Press. doi: 10.17226/9625.
×
Page 178
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Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries Get This Book
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Historically, 20% of all injured combatants die on the battlefield before they can be evacuated to a field hospital. Blood loss—hemorrhage—is the single major cause of death among those killed in action whose lives might otherwise be saved. Fluid resuscitation and the treatment of hypovolemia (the abnormally decreased volume of circulating fluid in the body) offer the greatest opportunity for reducing mortality and morbidity associated with battlefield casualties.

In Fluid Resuscitation, a committee of experts assess current resuscitation fluids and protocols for the treatment of combat casualties and make recommendations for future research. Chapters focus on the pathophysiology of acute hemorrhagic shock, experience with and complications of fluid resuscitation, novel approaches to the treatment of shock, protocols of care at the site of injury, and future directions for research.

The committee explicitly describes the similarities and differences between acute medical care during combat and civilian emergency trauma care. Fluid Resuscitation should help energize and focus research in both civilian and military emergency care and help save the lives of citizens and soldiers alike.

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