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Appendix C—
Biographies of Committee Members

Edward H. Shortliffe (chair) recently moved from Stanford University to Columbia University, where he serves as professor and chair of the Department of Medical Informatics. He also holds appointments as professor in the Medicine and Computer Science Departments. Dr. Shortliffe is a member of the Institute of Medicine and has served on the Computer Science and Telecommunications Board, the Federal Networking Advisory Committee (National Science Foundation), and the Biomedical Library Review Committee (National Library of Medicine) and was the recipient of a research career development award from the NLM. In 1993, he co-chaired a CSTB planning meeting on the role of information infrastructure in health care. He currently sits on the President's Information Technology Advisory Committee (PITAC). Dr. Shortliffe combines expertise in medicine and computer science. He received an A.B. in applied mathematics from Harvard College in 1970, a Ph.D. from Stanford in medical information sciences in 1975, and an M.D. at Stanford in 1976. During the early 1970s, he was principal developer of the medical expert system known as MYCIN. After a pause for internal medicine house-staff training at Harvard and Stanford between 1976 and 1979, he joined the Stanford internal medicine faculty, where he directed a research program in medical expert systems development. Dr. Shortliffe is interested in a broad range of issues related to integrated decision-support systems and their effective implementation. He spearheaded the formation of a Stanford degree program in medical informatics and at Columbia is continuing to divide his time between clinical medicine and medicalcontinue



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Page 334 Appendix C— Biographies of Committee Members Edward H. Shortliffe (chair) recently moved from Stanford University to Columbia University, where he serves as professor and chair of the Department of Medical Informatics. He also holds appointments as professor in the Medicine and Computer Science Departments. Dr. Shortliffe is a member of the Institute of Medicine and has served on the Computer Science and Telecommunications Board, the Federal Networking Advisory Committee (National Science Foundation), and the Biomedical Library Review Committee (National Library of Medicine) and was the recipient of a research career development award from the NLM. In 1993, he co-chaired a CSTB planning meeting on the role of information infrastructure in health care. He currently sits on the President's Information Technology Advisory Committee (PITAC). Dr. Shortliffe combines expertise in medicine and computer science. He received an A.B. in applied mathematics from Harvard College in 1970, a Ph.D. from Stanford in medical information sciences in 1975, and an M.D. at Stanford in 1976. During the early 1970s, he was principal developer of the medical expert system known as MYCIN. After a pause for internal medicine house-staff training at Harvard and Stanford between 1976 and 1979, he joined the Stanford internal medicine faculty, where he directed a research program in medical expert systems development. Dr. Shortliffe is interested in a broad range of issues related to integrated decision-support systems and their effective implementation. He spearheaded the formation of a Stanford degree program in medical informatics and at Columbia is continuing to divide his time between clinical medicine and medicalcontinue

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Page 335 informatics. Dr. Shortliffe is a member of the American Society for Clinical Investigation, the American Association of Physicians, and the American Clinical and Climatological Association. He has also been elected to fellowship in the American College of Medical Informatics and the American Association for Artificial Intelligence. He sits on the editorial boards of several medical computing and artificial intelligence publications. In addition, he received the Grace Murray Hopper Award of the Association for Computing Machinery in 1976 and has been a Henry J. Kaiser Family Foundation Faculty Scholar in General Internal Medicine. Dr. Shortliffe has authored over 180 articles and books in the fields of medical computing and artificial intelligence. Volumes include Computer-Based Medical Consultations: MYCIN (Elsevier/North-Holland, 1976), Readings in Medical Artificial Intelligence: the First Decade (with W.J. Clancey; Addison-Wesley, 1984), Rule-Based Expert Systems: The MYCIN Experiments of the Stanford Heuristic Programming Project (with B.G. Buchanan; Addison-Wesley, 1984), and Medical Informatics: Computer Applications in Health Care and Biomedicine (with L.E. Perreault, G. Wiederhold, and L.M. Fagan; Addison-Wesley, 1990; 2nd ed., Springer-Verlag, Spring 2000). Russ Biagio Altman is associate professor of medicine (and computer science by courtesy) at Stanford University. His primary research interests are in the application of computing technology to basic molecular biological problems of relevance to medicine. He is currently developing techniques for collaborative scientific computation over the Internet, including novel user interfaces to biological data. Other work focuses on the analysis of functional microenvironments within macromolecules and the application of nonlinear optimization algorithms for determining the structure and function of biological macromolecules, particularly the bacterial ribosome. He is on the executive committee (as Molecular Science Thrust leader) for the National Partnership for Advanced Computational Infrastructure (NPACI), the NSF-sponsored program at the San Diego Supercomputer Center. Dr. Altman holds an M.D. from Stanford Medical School, a Ph.D. in medical information sciences from Stanford, and an A.B. from Harvard College. He has been the recipient of the U.S. Presidential Early Career Award for Scientists and Engineers, a National Science Foundation CAREER Award, and the Western Society of Clinical Investigation Annual Young Investigator Award. He is a fellow of the American College of Physicians and the American College of Medical Informatics. Patricia Flatley Brennan is Moehlman Bascom Professor at the School of Nursing and College of Engineering at the University of Wisconsin. Dr. Brennan's research is in the area of nursing informatics and examinescontinue

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Page 336 ways to use the Internet, home-based computer systems, and specialized information resources to promote self-care and disease management skills among patients and their family caregivers. She earned a Ph.D. and an M.S. in industrial engineering from the University of Wisconsin at Madison, an M.S. in nursing from the University of Pennsylvania, and a B.S. in nursing from the University of Delaware. Bruce Davie works at Cisco Systems in Chelmsford, Massachusetts, where he is a Cisco Fellow. He received his B.E. (electrical) from the University of Melbourne, Australia, in 1984. He completed his Ph.D. in computer science at the University of Edinburgh, Scotland, in 1988 before starting work in the Computer Networking Research Department at Bell Communications Research (Bellcore) in Morristown, N.J. While at Bellcore, he worked on the Aurora gigabit testbed, the first wide-area gigabit network. At Bellcore he held the positions of director of Internetworking research and chief scientist and led research efforts on the Next Generation Internet Protocol, IP-over-ATM, and the support of real-time applications over the Internet. Dr. Davie joined Cisco Systems in 1995. He leads a group working on the development of multiprotocol label switching and quality-of-service capabilities for IP networks. He is the author of numerous journal articles, conference papers and book chapters, and three books on computer networks. He is an active member of both the Internet Engineering Task Force and the End-to-End research group. William M. Detmer is president and chief executive officer of a new Internet-based digital publishing company and is adjunct assistant professor of health evaluation sciences at the University of Virginia. He was formerly vice president of clinical information products for Ovid Technologies, Inc. Dr. Detmer's interests lie in the characterization of the knowledge needs of clinicians and the development of content, information science methods, and technologies that collectively meet those needs. In 1994 he developed WebMedline, the first World Wide Web interface to Medline, and he since has developed a variety of Internet-based applications and methods that bring medical knowledge to the point of care. Dr. Detmer holds a B.A. degree from the University of North Carolina at Chapel Hill, where he was a Morehead Scholar, an M.D. from the University of California San Francisco, and a master's degree in medical information science from Stanford University. He is board certified in internal medicine. Valerie Florance is project director for better_health@here.now, the information technology futures initiative of the Association of American Medical Colleges (AAMC), and principal investigator for IAIMS: The Nextcontinue

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Page 337 Generation, a state-of-the-art review of information management in academic health sciences centers. Before joining AAMC, she was director of academic information at the University of Rochester Medical Center. Dr. Florance has over 17 years of experience in health sciences libraries and information services at the University of Utah, Johns Hopkins, and the University of Rochester. She holds a B.A. in anthropology and an M.A. in medical anthropology from the University of Utah, an M.L.S. from Brigham Young University, and a Ph.D. in library and information science from the University of Maryland. She has served in a number of professional leadership roles, most recently as editor of Annual Statistics of Medical School Libraries in the United States and Canada. In 1995 and 1997, she won the Ida and George Eliot Prize from the Medical Library Association. Her scholarly interests center on technology, infrastructure, and policy issues in health sciences information management. Andrew Friede is a physician executive with the Cerner Corporation, a major supplier of health care information systems and services. Dr. Friede writes expert systems, designs information systems for medical researchers, and advises health care organizations on strategy. He was formerly at the Centers for Disease Control and Prevention (CDC), where he led the development of CDC WONDER, an integrated information and communications system that provides online access to over 30 public health databases, and has specialized features for CDC surveillance programs. His epidemiological research interests focused on maternal and child health conditions, including immunizations, injuries, infant and maternal mortality, teenage pregnancy, and obstetrical complications. He has been a consultant to the World Bank and the U.N. for public health and clinical information systems in China and Madagascar. He is the author of numerous publications and served as the chief editor of CDC Prevention Guidelines. Mark Frisse is vice president of clinical information services at Express Scripts, Inc., a pharmaceutical benefits management company. Until December 1999, he served as director of the Bernard Becker Medical Library; director of the Medical Informatics Laboratory; associate dean for Academic Information Management; professor of medicine, and academic director of the Health Services Management Executive M.B.A. Program in the John M. Olin School of Business at Washington University. In these roles he was responsible for a broad array of medical informatics research and teaching activities. John Glaser is vice president and chief information officer for Partners Healthcare System. He was founding chair of the College of Healthcarecontinue

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Page 338 Information Management Executives, is past president of the Healthcare Information Management Systems Society, and was the 1994 recipient of the John Gall award for health care chief information officer of the year. Dr. Glaser previously managed the health care information systems consulting practice at Arthur D. Little. He is the author of more than 40 publications on health information systems and holds a Ph.D. in health care information systems from the University of Minnesota. John Huffman is chief technology officer at Stentor, Inc., a company specializing in digital medical applications. He was previously in the Corporate Research and Development Group of Silicon Graphics Inc. (SGI) and managed its medical market technology and business development efforts. Mr. Huffman has concentrated on medical imaging applications for the last 10 years. Additional responsibilities while at SGI were the design and specification of next-generation processor and graphics architectures, development of image- and signal-processing methods, and numeric computation methods. Prior to joining SGI, Mr. Huffman was the cofounder and chief technology officer for Aware, Inc., where he developed image and video compression systems. Mr. Huffman holds several of the early wavelet patents in this field and wrote the only FDA-approved package for medical image compression. In addition, he worked on the development of adaptive signal processing methods, numeric solution of nonlinear partial differential equations, and video compression methods. Prior to joining Aware, Mr. Huffman spent two years working in the artificial intelligence group at the Microelectronics and Computer Technology Corporation under Doug Lenat, developing CYC, the largest, most comprehensive artificial intelligence system integrating all known methods into one reasoning system. Before that, Mr. Huffman was one of the original employees at Thinking Machines Corporation, where he designed the VLSI chip and contributed to microcoding the Connection Machine. Mr. Huffman also developed automated circuit placement methods that are in use in the industry today. Mr. Huffman began his professional career at the National Security Agency as a VLSI design engineer while performing graduate work in computer science and electrical engineering at the University of Maryland. He completed his undergraduate work in chemical physics at the University of Chicago in 1979. Isaac Kohane is director of the Children's Hospital Informatics Program in Boston and assistant professor of pediatrics at Harvard Medical School. Dr. Kohane was one of the lead developers of the W3EMRS system, a system that allows secure Internet-based sharing of medical information among emergency room doctors in five Boston-area hospitals. From 1995 to 1997, Dr. Kohane was leader of the Boston Collaborative Group forcontinue

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Page 339 Web access to electronic medical systems. He is currently working on the Health Information Identification and De-Identification Toolkit to enable the specification of health information systems with multiple trade-offs in confidentiality. He is also principal investigator of the Personal Internetworked Notary and Guardian project to enable patients to fully control their own medical records over multiple institutions from the Internet. Dr. Kohane earned a joint M.D./Ph.D. from Boston University in 1987 and a B.Sc. in biology from Brown University. He conducted his doctoral research in collaboration with the Clinical Decision Making Group in MIT's Laboratory for Computer Science, with which he maintains an affiliation. Carl E. Landwehr is a senior fellow and acting director of the Information Security Center at Mitretek Systems, a nonprofit center conducting research and development in the public interest. For many years, Dr. Landwehr headed the Computer Security Section of the Center for High Assurance Computer Systems at the U.S. Naval Research Laboratory. He has led a variety of research projects to advance technologies for computer security and high-assurance systems and has served on review panels for high-assurance research and development programs at the National Aeronautics and Space Administration and the National Security Agency. Dr. Landwehr serves as an expert consultant to the North Atlantic Treaty Organization and for 10 years chaired an international defense panel on secure information systems. The International Federation for Information Processing (IFIP) awarded him its Silver Core for his work as founding chair of IFIP Working Group 11.3 on database security, and the IEEE Computer Society awarded him its Golden Core for his work on behalf of its Technical Committee on Security and Privacy. He has served on the editorial boards of the High Integrity Systems Journal, IEEE Transactions on Software Engineering, and the Journal of Computer Security. Dr. Landwehr also served on the CSTB committee that produced the report For the Record: Protecting Electronic Health Information. He received a B.S. (engineering, 1968) from Yale University, an M.S. (computer and communication sciences, 1970) from the University of Michigan, and a Ph.D. (computer and communication sciences, 1974) from the University of Michigan. Daniel R. Masys is director of biomedical informatics at the University of California, San Diego School of Medicine, and associate clinical professor of medicine. An honors graduate of Princeton University and the Ohio State University College of Medicine, he completed postgraduate training in internal medicine, hematology, and medical oncology at the University of California at San Diego and the Naval Regional Medical Center, Sancontinue

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Page 340 Diego. He served as chief of the International Cancer Research Data Bank of the National Cancer Institute, National Institutes of Health, and from 1986 through 1994 was director of the Lister Hill National Center for Biomedical Communications, which is the computer research and development division of the National Library of Medicine. He also served as the NIH representative to the federal High Performance Computing, Communications, and Information Technology committee, which advised the President's Office of Science and Technology Policy in the area of advanced computing and national information infrastructure. Dr. Masys is a diplomate of the American Board of Internal Medicine in medicine, hematology, and medical oncology. He is a fellow of the American College of Physicians and a fellow of the American College of Medical Informatics. He is a founding associate editor of the Journal of the American Medical Informatics Association and has received numerous awards, including the NIH Director's Award, the Public Health Service Outstanding Service Medal, and the U.S. Surgeon General's Exemplary Service Medal. Dr. Masys' research interests are in Internet-accessible health information and information systems support for clinical research. He is co-principal investigator of the Patient-Centered Access to Secure Systems Online (PCASSO) research project funded by the National Library of Medicine, which is developing and evaluating a secure Web-based access method for clinical data. Jane E. Sisk is a professor in the Department of Health Policy and co-director of the Center for Evidence-Based Medicine and Aging at Mount Sinai School of Medicine in New York City. She was formerly a professor in the Division of Health Policy and Management and director of the Master's Program in Effectiveness and Outcomes Research at Columbia University School of Public Health. Before joining Columbia, she directed projects at the Congressional Office of Technology Assessment as a senior associate and project director in the Health Program. She also served as president, International Society of Technology Assessment in Health Care, of which she was a founding member. Dr. Sisk is a fellow of the Association for Health Services Research and sits on the editorial boards of Health Services Research and the International Journal of Technology Assessment in Health Care. She served on the IOM committee that produced the report Telemedicine: A Guide to Assessing Telecommunications in Health Care and is currently a member of the IOM Committee on Immunization Finance Policies and Practices and the NRC-IOM National Cancer Policy Board. Dr. Sisk earned a B.A. in international relations (Phi Beta Kappa, magna cum laude) from Brown University, an M.A. in economics from George Washington University, and a Ph.D. in economics from McGill University.break

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Page 341 Thorsten Von Eicken is assistant professor of computer science at Cornell University. His research has focused on high-performance communication in clusters of workstations and developed the U-Net user-level networking architecture to close the dramatic gap between the bit rate of high-speed networks and the communication performance seen by applications. He recently started a new project: the Safe Language Kernel (SLK), which is an operating system infrastructure for customizable Internet servers and application-specific gateways. The primary goal of SLK is to allow users to download custom services into servers in the network in a secure yet flexible manner. Just as Java enables Web browsers in which users safely download applets, SLK will enable safe Internet servers into which users can upload servlets. Dr. Von Eicken received his Ph.D. from the University of California at Berkeley. He was the recipient of an NSF CAREER Award in 1997. He has published widely on high-performance computing architectures, parallel computing/programming, and low-latency data communications.break