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DRI DIETARY REFERENCE INTAKES FOR Vitamin C, Vitamin E, Selenium, and Carotenoids
TABLE 6-2 continued
Reference
Country
Subjects
Clinical Features
Gotoda et al., 1995
Japan
n = 1 male; aged 62 (aged 52 at onset)
Unsteadiness in the dark
Slurred and scanning speech
Moderate ataxia in all extremities
Flexor plantar responses
Reduced reaction to touch and pinprick
No joint position sense in toes
Broad-based and ataxic gait
Romberg sign
No knee or ankle reflexes
Numbness in fingers and toes
Kohlschütter et al., 1988
Germany
n = 1 male; aged 19
Ataxia
Sensory neuropathy
Lipopigment deposition
Sokol et al., 1988
United States
n = 1 male and 3 females; aged 21–30
Head titubation
Intention tremor in hand
Difficulty walking
Progressive ataxia
Dysarthria
Vibratory and sensory loss
Incontinence
Pes cavus
Position sense loss
Trabert et al., 1989
Germany
n = 1 male; aged 26
Cerebellar ataxia
No tendon reflexes in lower limbs
Vibration sense disturbances
Babinsky sign
Head titubation
Ben Hamida et al., 1993
Tunisia
n = 7 Friedreich's ataxia patients; aged 21–34
Severe cerebellar ataxia
Severe dysarthria
Slight deep sensory loss
Slight Babinski signs
Slight Pes cavus
Slight kyphoscoliosis
Absent to moderate cardiomyopathyf
Front Matter (R1-R23)
Summary (1-20)
1 Introduction to Dietary Reference Intakes (21-34)
2 Vitamin C, Vitamin E, Selenium, and •-Carotene and Other Carotenoids: Overview, Antioxidant Definition, and Relationship to Chronic Disease (35-57)
3 Vitamin C, Vitamin E, Selenium, and •-Carotene and Other Carotenoids: Methods (58-72)
4 A Model for the Development of Tolerable Upper Intake Levels for Nutrients (73-94)
5 Vitamin C (95-185)
6 Vitamin E (186-283)
7 Selenium (284-324)
8 •-Carotene and Other Carotenoids (325-382)
9 Uses of Dietary Reference Intakes (383-400)
10 A Research Agenda (401-408)
A Origin and Framework of the Development of Dietary Reference Intakes (409-412)
B Acknowledgments (413-415)
C Dietary Intake Data from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994 (416-431)
D Dietary Intake Data from the Continuing Survey of Food Intakes by Individuals (CSFII), 1994–1996 (432-437)
E Canadian Dietary Intake Data, 1993, 1995 (438-439)
F Serum Values from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994 (440-457)
G Options for Dealing with Uncertainties (458-462)
H Glossary and Acronyms (463-468)
I Biographical Sketches of Panel and Subcommittee Members (469-482)
Index (483-506)
