The process described below is expected to be used for subsequent reports as well.

The Panel on Dietary Antioxidants and Related Compounds, composed of experts on these nutrients, has been responsible for the following: (1) propose a definition of a dietary antioxidant; (2) review the scientific literature concerning antioxidant nutrients and selected components of foods that may influence the bioavailability of these nutrients; (3) develop dietary reference levels of intake for the selected dietary antioxidants that are compatible with good nutrition throughout the life span and that may decrease the risk of developmental abnormalities and chronic disease; (4) address the safety of high intakes of these dietary antioxidants and, when appropriate, determine Tolerable Upper Intake Levels (ULs); and (5) identify a research agenda to provide a basis for public policy decisions related to recommended intakes and ways to achieve these intakes.

The panel was charged with analyzing the literature, evaluating possible criteria or indicators of adequacy, and providing substantive rationales for their choices of each criterion. Using the criterion chosen for each stage of the lifespan, the panel estimated the average requirement for each nutrient or food component reviewed, assuming that adequate data were available. As panel members reviewed data on ULs, they interacted with the Subcommittee on Upper Reference Levels of Nutrients, which assisted the panel in applying the risk assessment model to each selected nutrient. The panel also worked with the Subcommittee on Interpretation and Uses of Dietary Reference Intakes to determine appropriate examples for using the Recommended Dietary Allowances, Estimated Average Requirements, Adequate Intakes, and ULs. The Dietary Reference Intake values in this report are a product of the joint efforts of the DRI Committee, the Panel on Dietary Antioxidants and Related Compounds, the Subcommittee on Upper Reference Levels of Nutrients, and the Subcommittee on Interpretation and Uses of Dietary Reference Intakes, all under the oversight of the Food and Nutrition Board.

REFERENCES

COMA (Committee on Medical Aspects of Food Policy). 1991. Dietary Reference Values for Food Energy and Nutrients for the United Kingdom. Report on Health and Social Subjects, No. 41. London: Her Majesty's Stationery Office.

Health Canada. 1990. Nutrition Recommendations. The Report of the Scientific Review Committee 1990. Ottawa: Canadian Government Publishing Centre.

IOM (Institute of Medicine). 1994. How Should the Recommended Dietary Allowances be Revised? Washington, DC: National Academy Press.



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