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Toxicological Risks of Selected Flame-Retardant Chemicals
Boric Acid
The weight of evidence indicates that boron compounds are not genotoxic (Table 8–4).
TABLE 8–4 Genotoxicity of Boron Compounds
Test System
Boron Compound
Genotoxicity End Point
Result
Reference
Escherichia coli Blr/Scl-4
Boric acid
Gene mutations
Positive
Demerec et al. 1951
Salmonella typhimuirum
Boric acid, borax
Gene mutations
Negative
NTP 1987
Salmonella typhimuirum
Boric acid
Gene mutations
Negative
Stewart 1991
Human fibroblasts
Borax
Gene mutations
Negative
Landolph 1985
V79 Chinese hamster ovary cells
Borax
Gene mutations
Weakly positive
Landolph 1985
C3H/10T1/2
Borax
Gene mutations
Negative
Landolph 1985
Chinese hamster ovary cells
Boric acid, borax
Sister-chromatid exchange and chromosomal aberrations
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