TABLE 4–1 Physical and Chemical Properties of HBCD

Property	Value	Reference
Chemical formula	C12H18Br6	CHEMID 1999
Chemical structure
CAS Registry #	25637–99–4 (mixed isomers)	CHEMID 1999
Molecular weight	641.7	Hatlelid 1999
Melting point	185–195°C	Hatlelid 1999
Vapor pressure	4.7×10−7 mm Hg	Stenzel and Nixon 1997
Density	2.24 g/cm3	Hatlelid 1999
Solubility in water	0.0034 mg/L	Stenzel and Markley 1997
Partition coefficient (Log Kow)	5.6	MacGregor and Nixon 1997

holstery seating in transportation, draperies, and wall coverings (FRCA 1998). HBCD is usually applied with antimony trioxide as a back coating in a mass ratio of 2:1 (i.e., about 6–15% HBCD and 4–10% antimony oxide by weight).

No human data on the toxicokinetics of HBCD were located for any route. No toxicokinetic studies via the dermal or inhalation exposure routes were reported in experimental animals. However, in a report by Dean and Leong (1977), rats exposed dermally to a high dose of HBCD in saline experienced diarrhea and slight weight loss. This finding indicates that at least some absorption occurs via the dermal route.

In an unpublished study by Vesicol Chemical Corporation (1980), rats