Cover Image

PAPERBACK
$15.00



View/Hide Left Panel

Developing Technologies for Early Detection of Breast Cancer

A Public Workshop Summary

Written by Laura Newman, M.A. Medical Writer

For the

Committee on the Early Detection of Breast Cancer

National Cancer Policy Board

INSTITUTE OF MEDICINE

and

COMMISSION ON LIFE SCIENCES

NATIONAL RESEARCH COUNCIL

NATIONAL ACADEMY PRESS
Washington, D.C.



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement



Below are the first 10 and last 10 pages of uncorrected machine-read text (when available) of this chapter, followed by the top 30 algorithmically extracted key phrases from the chapter as a whole.
Intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text on the opening pages of each chapter. Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.

Do not use for reproduction, copying, pasting, or reading; exclusively for search engines.

OCR for page R1
Developing Technologies for Early Detection of Breast Cancer: A Public Workshop Summary Developing Technologies for Early Detection of Breast Cancer A Public Workshop Summary Written by Laura Newman, M.A. Medical Writer For the Committee on the Early Detection of Breast Cancer National Cancer Policy Board INSTITUTE OF MEDICINE and COMMISSION ON LIFE SCIENCES NATIONAL RESEARCH COUNCIL NATIONAL ACADEMY PRESS Washington, D.C.

OCR for page R1
Developing Technologies for Early Detection of Breast Cancer: A Public Workshop Summary NATIONAL ACADEMY PRESS 2101 Constitution Avenue, N.W. Washington, DC 20418 NOTICE: The project that is the subject of this report was approvedby the Governing Board of the National Research Council, whose membersare drawn from the councils of the National Academy of Sciences,the National Academy of Engineering, and the Institute of Medicine.The members of the committee responsible for the report were chosenfor their special competences and with regard for appropriate balance. Support for this project was provided by The Breast Cancer ResearchFoundation, the Carl J. Herzog Foundation, Mr. John K. Castle, theJewish Healthcare Foundation (Pittsburgh), the Josiah Macy, Jr.,Foundation, the Kansas Health Foundation, and the New York CommunityTrust. The views presented in this Workshop Summary are those ofthe workshop speakers, and are not necessarily those of the Instituteof Medicine Committee on Technologies for Early Detection of BreastCancer or of the sponsors. International Standrad Book. Number 0-309-07135-6 Additional copies of this Workshop Summary are available for salefrom the National Academy Press , Box 285, 2101 Constitution Avenue, N.W.,Washington, DC20055; call (800) 624-6242 or (202) 334-3313 (in the Washington metropolitan area), or visit the NAP's on-line bookstore at www.nap.edu. The full text of this Workshop Summary is available on line at www.nap.edu. For more information about the Institute of Medicine, visit the IOMhome page at www.iom.edu. Copyright 2000 by the National Academy of Sciences. All rights reserved. Printed in the United States of America. The serpent has been a symbol of long life, healing, and knowledgeamong almost all cultures and religions since the beginning of recordedhistory. The serpent adopted as a logotype by the Institute of Medicineis a relief carving from ancient Greece, now held by the StaatlicheMuseen in Berlin.

OCR for page R1
Developing Technologies for Early Detection of Breast Cancer: A Public Workshop Summary “Knowing is not enough; we must apply. Willing is not enough; we must do.” —Goethe INSTITUTE OF MEDICINE Shaping the Future for Health

OCR for page R1
Developing Technologies for Early Detection of Breast Cancer: A Public Workshop Summary THE NATIONAL ACADEMIES National Academy of Sciences National Academy of Engineering Institute of Medicine National Research Council The National Academy of Sciences is a private, nonprofit, self-perpetuating society of distinguishedscholars engaged in scientific and engineering research, dedicatedto the furtherance of science and technology and to their use forthe general welfare. Upon the authority of the charter granted toit by the Congress in 1863, the Academy has a mandate that requiresit to advise the federal government on scientific and technical matters.Dr. Bruce M. Alberts is president of the National Academy of Sciences. The National Academy of Engineering was established in 1964, under the charter of the National Academyof Sciences, as a parallel organization of outstanding engineers.It is autonomous in its administration and in the selection of itsmembers, sharing with the National Academy of Sciences the responsibilityfor advising the federal government. The National Academy of Engineeringalso sponsors engineering programs aimed at meeting national needs,encourages education and research, and recognizes the superior achievementsof engineers. Dr. William A. Wulf is president of the National Academyof Engineering. The Institute of Medicine was established in 1970 by the National Academy of Sciences to securethe services of eminent members of appropriate professions in theexamination of policy matters pertaining to the health of the public.The Institute acts under the responsibility given to the NationalAcademy of Sciences by its congressional charter to be an adviserto the federal government and, upon its own initiative, to identifyissues of medical care, research, and education. Dr. Kenneth I. Shineis president of the Institute of Medicine. The National Research Council was organized by the National Academy of Sciences in 1916 to associatethe broad community of science and technology with the Academy'spurposes of furthering knowledge and advising the federal government.Functioning in accordance with general policies determined by theAcademy, the Council has become the principal operating agency ofboth the National Academy of Sciences and the National Academy ofEngineering in providing services to the government, the public,and the scientific and engineering communities. The Council is administeredjointly by both Academies and the Institute of Medicine. Dr. BruceM. Alberts and Dr. William A. Wulf are chairman and vice chairman,respectively, of the National Research Council.

OCR for page R1
Developing Technologies for Early Detection of Breast Cancer: A Public Workshop Summary COMMITTEE ON TECHNOLOGIES FOR THE EARLY DETECTION OF BREAST CANCER JOYCE C. LASHOF, M.D., FACP (Chair), Professor Emerita, School of Public Health, University of California at Berkeley I. CRAIG HENDERSON, M.D. (Vice Chair), Senior Medical Consultant and Director, Adjunct Professor of Medicine, ALZA Corporation, and University of California at San Francisco DANIEL F. HAYES, M.D., Clinical Director, Breast Cancer Program, Lombardi Cancer Center, Georgetown University Medical Center LEON GORDIS, M.D., D.P.H., Director, Professor of Epidemiology, Clinical Epidemiology, Johns Hopkins School of Medicine, and Johns Hopkins School of Public Health and Hygiene JEAN J. LATIMER, Ph.D., Investigator, Assistant Professor, Magee-Womens Research Institute, and Department. of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh D. CRAIG ALLRED, M.D., Professor of Pathology, Baylor College of Medicine KENNETH OFFIT, M.D., M.P.H., Chief, Clinical Genetics Service, Department of Human Genetics, Memorial Sloan-Kettering Cancer Center, New York City JANET K. BAUM, M.D., F.A.C.R., Associate Professor of Radiology, Director, Harvard Medical School, and Breast Imaging, Beth Israel Deaconess Hospital, Boston MICHAEL W. VANNIER, M.D., Professor and Head, Department of Radiology, University of Iowa College of Medicine FAINA SHTERN, M.D., Director, Office of Research Affairs, Department of Radiology, Beth Israel-Deaconess Medical Center, and Harvard Medical School CAROLINA HINESTROSA, M.A., Cofounder and Program Director, Nueva Vida WADE M. AUBRY, M.D., Vice President, Health Care Organizations and Medical Technology Practices, the Lewin Group, Fairfax, Virginia DEREK VAN AMERONGEN, M.D., M.S., FACOG, National Medical Director, Anthem Blue Cross and Blue Shield, Cincinnati, Ohio SUZANNE W. FLETCHER, M.D., Professor, Harvard School of Medicine and School of Public Health, Brigham and Women's Hospital, Boston MARTHE R. GOLD, M.D., M.P.H., Chair, Department of Community Health and Social Medicine, City University of New York Medical School RICHARD R. NELSON, Ph.D., George Blumenthal Professor of International and Public Affairs, School of Law, Columbia University Liaison for the National Cancer Policy Board ROBERT DAY, M.D., M.P.H., Ph.D., Emeritus President and Director, Fred Hutchinson Cancer Research Center Staff SHARYL J. NASS, Ph.D., Study Director ROBERT COOK-DEEGAN, M.D., Director, National Cancer Policy Board CARMIE CHAN, Research Assistant BIANCA L. TAYLOR, Project Assistant ELLEN JOHNSON, Administrative Assistant JOHN KUCEWICZ, Intern

OCR for page R1
Developing Technologies for Early Detection of Breast Cancer: A Public Workshop Summary This page in the original is blank.

OCR for page R1
Developing Technologies for Early Detection of Breast Cancer: A Public Workshop Summary REVIEWERS The report was reviewed by individuals chosen for their diverse perspectivesand technical expertise in accordance with procedures approved bythe National Research Council's Report Review Committee. The purposeof this independent review is to provide candid and critical commentsto assist the authors and the Institute of Medicine in making thepublished report as sound as possible and to ensure that the reportmeets institutional standards for objectivity, evidence, and responsivenessto the study charge. The content of the review comments and the draftmanuscript remain confidential to protect the integrity of the deliberativeprocess. The committee wishes to thank the following individualsfor their participation in the report review process: David G. Bragg, M.D., FACR, Professor Emeritus, University of Utah School of Medicine Thomas F. Budinger, M.D., Ph.D., Head, Center for Functional Imaging, E. O. LawrenceBerkeley National Laboratory, University of California at Berkeley R. Edward Hendrick, Ph.D., Research Professor and Director, Breast Imaging Research,The Lynn Sage Comprehensive Breast Center, Northwestern UniversityMedical School J. Dirk Iglehart, M.D., Professor of Surgery, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston While the individuals listed above provided many constructive commentsand suggestions, responsibility for the final content of the reportrests solely with the author and the Institute of Medicine.

OCR for page R1
Developing Technologies for Early Detection of Breast Cancer: A Public Workshop Summary This page in the original is blank.