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Toxicological Effects of Methylmercury (2000)
Commission on Life Sciences (CLS)

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Toxicological Effects of Methylmercury

TABLE 8-3 Population Margins of Exposure (MOE)a for Selected BMDLs and Exposure Estimates (ppm of Hg in Maternal Hair or Estimated Equivalent to Maternal Hair)

   

MOE
   

Estimated MeHg Exposure in Selected Populations
   

New Jersey Pregnant Women b

EPA Region V Populationc

U.S. Women of Childbearing Aged

Study

Selected BMDL (value, ppm)

Mean

(0.53)

95th Percentile

(2.0)

Mean

(0.29)

95thPercentile (1)

Mean

(0.36)

95th Percentile

(2.4)

New Zealand

Most sensitive (4)

7.5

2.0

13.8

4

11.1

1.7

Faroe Islands

Most sensitive (10)

18.9

5.0

34.5

10

27.8

4.2

Faroe Islands

Most-sensitive-reliable, cord-blood derived (12)

22.6

6.0

41.4

12

33.3

5.0

Seychelles

Median (22)

41.5

11

77.3

22

61.1

9.2

New Zealand, Faroe Islands, and Seychelles (integrative analysis)

Lower 5% (7)

13.2

3.5

24.1

7

19.4

2.9

Iraq

(11)e

20.8

5.5

37.9

11

30.6

4.6

aMOE, BMDL/exposure estimate.

bData from Stern et al. 2000.

cData from Pellizzari et al. 1999.

dData from Smith et al. 1997.

eCurrent RfD basis.

Abbreviations: BMDL, lower 95% confidence limit on the benchmark dose; RfD, reference dose.
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