TABLE G-1 Among Service Members Receiving at Least One Dose of AVA Hospitalization Diagnoses with Rate Ratios Above 1.0, U.S. Armed Forces, Active Duty, 1998 to 2000
ICD-9-CM Code(s) |
Description |
Anthrax Immunization Status |
Adjusted Rate Ratio |
95% Confidence Intervals |
||||
Post |
Pre |
|||||||
Number |
Rate per 100,000 |
Number |
Rate per 100,000 |
|||||
193 |
Malignant neoplasm of thyroid gland |
41 |
5.6 |
9 |
1.9 |
2.40 |
1.05 |
5.49 |
233 |
Carcinoma in situ of breast and genitourinary system |
19 |
2.6 |
5 |
1.0 |
5.14 |
1.81 |
14.57 |
250 |
Diabetes mellitus |
67 |
9.1 |
8 |
1.7 |
3.46 |
1.51 |
7.90 |
296 |
Affective psychoses |
600 |
81.3 |
120 |
25.1 |
2.15 |
1.71 |
2.71 |
298 |
Other nonorganic psychoses |
69 |
9.3 |
14 |
2.9 |
2.50 |
1.29 |
4.83 |
309 |
Adjustment reaction |
1,219 |
165.1 |
403 |
84.3 |
1.38 |
1.20 |
1.59 |
311 |
Depressive disorder, not elsewhere classified |
187 |
22.6 |
46 |
9.6 |
1.79 |
1.21 |
2.66 |
374 |
Other disorders of eyelids |
16 |
2.2 |
7 |
1.5 |
2.71 |
1.05 |
7.00 |
550 |
Inguinal hemia |
293 |
39.7 |
172 |
35.0 |
1.31 |
1.04 |
1.65 |
569 |
Other disorders of intestine |
34 |
4.6 |
6 |
1.3 |
2.94 |
1.23 |
7.07 |
724 |
Other and unspecified disorders of back |
108 |
14.6 |
38 |
7.9 |
1.51 |
1.04 |
2.20 |
726 |
Peripheral enthesopathies and allied syndromes |
213 |
28.8 |
97 |
20.3 |
1.29 |
1.01 |
1.64 |
732 |
Osteochondropathies |
38 |
5.1 |
11 |
2.3 |
2.03 |
1.03 |
3.98 |
808 |
Fracture of pelvis |
53 |
7.2 |
16 |
3.3 |
1.81 |
1.03 |
3.20 |
823 |
Fracture of tibia and fibula |
169 |
22.9 |
60 |
12.5 |
1.63 |
1.14 |
2.32 |
TABLE G-2 Among Service Members Receiving at Least One Dose of AVA, Hospitalization Diagnoses with Rate Ratios Above 1.0, by Number of Days after Immunization, U.S. Armed Forces, Active Duty, 1998 to 2000
ICD-9-CM Code(s) |
Description |
Anthrax immunization Status |
Comparison* |
||||||||||
Pre |
0-45 days |
>45days |
0-45/Pre |
>45/Pre |
|||||||||
Number |
Rate per 100,000 |
Number |
Rate per 100,000 |
Number |
Rate per 100,000 |
Adjusted Rate Ratio |
98% CI |
Adjusted Rate Ratio |
95% CI |
||||
193 |
Malignant neoplasm of thyroid gland |
9 |
1.88 |
10 |
6.04 |
31 |
5.41 |
2.88 |
1.12 |
7.37 |
2.16 |
0.90 |
5.17 |
220 |
Benign neoplasm of ovary |
9 |
1.88 |
8 |
4.83 |
12 |
2.10 |
2.61 |
1.01 |
6.77 |
1.13 |
0.48 |
2.68 |
233 |
Carcinoma in situ of breast and genitourinary system |
5 |
1.05 |
5 |
3.02 |
14 |
2.44 |
4.12 |
1.17 |
14.49 |
5.85 |
1.95 |
17.58 |
250 |
Diabetes mellitus |
8 |
1.67 |
13 |
7.85 |
54 |
9.43 |
3.49 |
1.39 |
8.79 |
3.44 |
1.47 |
8.06 |
296 |
Affective psychoses |
120 |
25.10 |
102 |
61.56 |
498 |
86.96 |
1.84 |
1.39 |
2.43 |
2.31 |
1.82 |
2.94 |
298 |
Other nonorganic psychoses |
14 |
2.93 |
9 |
5.43 |
60 |
10.48 |
1.52 |
0.64 |
3.62 |
3.08 |
1.55 |
6.13 |
304 |
Drug dependence |
6 |
1.25 |
2 |
1.21 |
33 |
5.76 |
. |
. |
. |
3.06 |
1.08 |
8.66 |
309 |
Adjustment reaction |
403 |
84.29 |
258 |
155.72 |
961 |
167.80 |
1.37 |
1.16 |
1.62 |
1.38 |
1.19 |
1.61 |
311 |
Depressive disorder, not elsewhere classified |
46 |
9.62 |
35 |
21.12 |
132 |
23.05 |
1.78 |
1.11 |
2.84 |
1.80 |
1.19 |
2.72 |
312 |
Disturbance of conduct, not elsewhere classified |
6 |
1.25 |
0 |
0.00 |
12 |
2.10 |
. |
. |
. |
1.41 |
1.41 |
1.41 |
414 |
Other forms of chronic ischemic heart disease |
18 |
3.76 |
20 |
12.07 |
81 |
14.14 |
2.15 |
1.09 |
4.23 |
1.65 |
0.89 |
3.07 |
429 |
III-defined desoriptions and complications of heart disease |
6 |
1.25 |
0 |
0.00 |
12 |
2.10 |
. |
. |
. |
1.32 |
1.32 |
1.32 |
451 |
Phlebitis and thrombophlebitis |
5 |
1.05 |
0 |
0.00 |
12 |
2.10 |
. |
. |
. |
1.58 |
1.58 |
1.58 |
470 |
Deviated nasal septum |
45 |
9.41 |
23 |
13.88 |
90 |
15.72 |
1.19 |
0.72 |
1.97 |
1.47 |
1.02 |
2.11 |
493 |
Asthma |
41 |
8.58 |
30 |
18.11 |
64 |
11.18 |
1.83 |
1.14 |
2.93 |
1.10 |
0.74 |
1.64 |
541 |
Appendicitis, unqualified |
47 |
9.83 |
19 |
11.47 |
77 |
13.45 |
1.15 |
0.68 |
1.97 |
1.46 |
1.01 |
2.11 |
550 |
Inguinal hernia |
172 |
35.98 |
76 |
45.87 |
217 |
37.89 |
1.24 |
0.93 |
1.65 |
1.36 |
1.05 |
1.76 |
569 |
Other disorders of intestine |
6 |
1.25 |
10 |
6.04 |
24 |
4.19 |
4.16 |
1.51 |
11.49 |
2.61 |
1.06 |
6.44 |
598 |
Urethral stricture |
22 |
5.18 |
8 |
5.38 |
51 |
9.89 |
0.96 |
0.43 |
2.16 |
1.66 |
1.00 |
2.75 |
622 |
Noninflammatory disorders of cervix |
15 |
28.20 |
22 |
129.54 |
48 |
84.26 |
2.64 |
1.30 |
5.35 |
1.55 |
0.78 |
3.09 |
724 |
Other and unspecified disorders of back |
38 |
7.95 |
19 |
11.47 |
89 |
15.54 |
1.25 |
0.72 |
2.18 |
1.59 |
1.08 |
2.33 |
733 |
Other disorders of bone and cartilage |
95 |
19.87 |
45 |
27.16 |
194 |
33.87 |
1.12 |
0.77 |
1.62 |
1.45 |
1.06 |
1.98 |
735 |
Acquired deformities of toe |
34 |
7.11 |
20 |
12.07 |
83 |
14.49 |
1.15 |
0.66 |
2.01 |
1.58 |
1.06 |
2.37 |
808 |
Fracture of pelvis |
16 |
3.35 |
11 |
6.64 |
42 |
7.33 |
1.66 |
0.77 |
3.60 |
1.86 |
1.04 |
3.34 |
823 |
Fracture of tibia and fibula |
60 |
12.55 |
36 |
21.73 |
133 |
23.22 |
1.53 |
0.99 |
2.37 |
1.68 |
1.15 |
2.46 |
865 |
Injury to spleen |
9 |
1.88 |
10 |
6.04 |
19 |
3.32 |
2.83 |
1.15 |
6.99 |
1.61 |
0.72 |
3.58 |
999 |
Complications of medical care, not elsewhere classified |
7 |
1.46 |
5 |
3.02 |
5 |
0.87 |
3.70 |
1.05 |
13.04 |
1.25 |
0.30 |
5.11 |
TABLE G-3 Among Service Members Receiving at Least One Dose of AVA, Hospitalization Diagnoses with Rate Ratios Above 1.0, by Number of Doses After Immunization, U.S. Armed Forces, Active Duty, 1998 to 2000
|
Anthrax Immunization Status |
Comparison |
|||||||||
Pre |
1 to 3 doses |
4 or more doses |
1 to 3 doses/Pre |
4 or more/Pre |
|||||||
ICD-9-CM |
Description |
Number |
Rate/100,000 |
Number |
Rate/100,000 |
Number |
Rate/100,000 |
Adjusted Rate ratio |
95% CI |
Adjusted Rate ratio |
95% CI |
193 |
Malignant neoplasm of thyroid gland |
9 |
1.88 |
12 |
6.51 |
29 |
5.23 |
2.55 |
0.94-6.94 |
2.35 |
1.01-5.48 |
225 |
Benign neoplasm of brain and other parts of nervous system |
6 |
1.25 |
8 |
4.34 |
6 |
1.08 |
2.99 |
1.02-8.77 |
0.70 |
0.22-2.19 |
250 |
Diabetes mellitus |
8 |
1.67 |
24 |
13.02 |
43 |
7.76 |
4.98 |
2.02-12.25 |
3.05 |
1.31-7.09 |
296 |
Affective psychoses |
120 |
25.10 |
229 |
124.27 |
371 |
66.95 |
3.65 |
2.81-4.74 |
1.79 |
1.42-2.27 |
298 |
Other nonorganic psychoses |
14 |
2.93 |
26 |
14.11 |
43 |
7.76 |
4.08 |
1.92-8.68 |
2.11 |
1.07-4.18 |
300 |
Neurotic disorders |
69 |
14.43 |
70 |
37.99 |
101 |
18.23 |
2.20 |
1.46-3.30 |
0.92 |
0.64-1.32 |
301 |
Personality disorders |
64 |
13.39 |
115 |
62.41 |
81 |
14.62 |
1.95 |
1.32-2.87 |
0.69 |
0.46-1.02 |
304 |
Drug dependence |
6 |
1.25 |
13 |
7.05 |
22 |
3.97 |
4.20 |
1.37-12.91 |
1.81 |
0.64-5.07 |
309 |
Adjustment reaction |
403 |
84.29 |
460 |
249.63 |
759 |
136.98 |
2.28 |
1.94-2.69 |
1.16 |
1.00-1.34 |
311 |
Depressive disorder, not elsewhere classified |
46 |
9.62 |
49 |
26.59 |
118 |
21.30 |
2.60 |
1.62-4.20 |
1.63 |
1.09-2.44 |
346 |
Migraine |
36 |
7.53 |
30 |
16.28 |
46 |
8.30 |
1.82 |
1.12-2.98 |
0.90 |
0.58-1.40 |
348 |
Other conditions of brain |
7 |
1.46 |
9 |
4.88 |
8 |
1.44 |
2.80 |
1.03-7.63 |
0.78 |
0.28-2.19 |
410 |
Acute myocardial infarction |
22 |
4.60 |
24 |
13.02 |
44 |
7.94 |
2.60 |
1.42-4.75 |
1.15 |
0.69-1.94 |
470 |
Deviated nasal septum |
45 |
9.41 |
18 |
9.77 |
95 |
17.14 |
1.15 |
0.65-2.00 |
1.47 |
1.02-2.10 |
493 |
Asthma |
41 |
8.58 |
36 |
19.54 |
58 |
10.47 |
2.18 |
1.37-3.47 |
1.00 |
0.67-1.51 |
550 |
Inguinal hernia |
172 |
35.98 |
55 |
29.85 |
238 |
42.95 |
1.24 |
0.88-1.75 |
1.32 |
1.04-1.68 |
555 |
Regional enteritis |
5 |
1.05 |
19 |
10.31 |
20 |
3.61 |
4.90 |
1.55-15.44 |
1.96 |
0.65-5.95 |
569 |
Other disorders of intestine |
6 |
1.25 |
6 |
3.26 |
28 |
5.05 |
2.05 |
0.66-6.41 |
3.24 |
1.33-7.89 |
724 |
Other and unspecified disorders of back |
38 |
7.95 |
26 |
14.11 |
82 |
14.80 |
1.78 |
1.06-2.98 |
1.45 |
0.98-2.13 |
726 |
Peripheral enthesopathies and allied syndromes |
97 |
20.29 |
57 |
30.93 |
156 |
28.15 |
1.49 |
1.07-2.09 |
1.04 |
0.80-1.34 |
732 |
Osteochondropathies |
11 |
2.30 |
6 |
3.26 |
32 |
5.78 |
1.50 |
0.55-4.12 |
2.17 |
1.09-4.32 |
733 |
Other disorders of bone and cartilage |
95 |
19.87 |
68 |
36.90 |
171 |
30.86 |
1.77 |
1.22-2.56 |
1.23 |
0.91-1.66 |
735 |
Acquired deformities of toe |
34 |
7.11 |
12 |
6.51 |
91 |
16.42 |
0.93 |
0.48-1.82 |
1.60 |
1.07-2.39 |
808 |
Fracture of pelvis |
16 |
3.35 |
15 |
8.14 |
38 |
6.86 |
2.47 |
1.20-5.09 |
1.64 |
0.91-2.98 |
813 |
Fracture of radius and ulna |
102 |
21.33 |
54 |
29.30 |
114 |
20.57 |
1.62 |
1.10-2.37 |
1.13 |
0.83-1.54 |
823 |
Fracture of tibia and fibula |
60 |
12.55 |
50 |
27.13 |
119 |
21.48 |
1.93 |
1.24-3.01 |
1.55 |
1.07-2.23 |
844 |
Sprains and strains of knee and leg |
113 |
23.64 |
64 |
34.73 |
167 |
30.14 |
1.67 |
1.22-2.29 |
1.10 |
0.86-1.39 |
851 |
Cerebral laceration and contusion |
8 |
1.67 |
2 |
1.09 |
22 |
3.97 |
- |
- |
2.43 |
1.08-5.47 |
891 |
Open wound of knee, leg [ except thigh ], and ankle |
18 |
3.76 |
18 |
9.77 |
28 |
5.05 |
2.10 |
1.08-4.11 |
1.26 |
0.70-2.29 |
998 |
Other complications of procedures, not elsewhere classified |
157 |
32.84 |
112 |
60.78 |
250 |
45.12 |
1.51 |
1.13-2.02 |
1.11 |
0.87-1.41 |
TABLE G-4 Among all Service Members, Hospitalization Diagnoses with Rate Ratios Above 1.0, U.S. Armed Forces, Active Duty, 1998 to 2000
ICD-9-CM Code(s) |
Description |
Anthrax Immunization Status |
Adjusted Rate Ratio |
95% Confidence Intervals |
||||
Pre |
Never |
|||||||
Number |
Rate per 100,000 |
Number |
Rate per 100,000 |
|||||
084 |
Malaria |
18 |
3.8 |
62 |
2.1 |
1.76 |
1.04 |
2.99 |
695 |
Erythematous conditions |
9 |
1.9 |
22 |
0.8 |
2.74 |
1.25 |
6.00 |
913 |
Superficial injury of elbow, forearm, and wrist |
10 |
2.1 |
17 |
0.6 |
3.37 |
1.53 |
7.45 |
986 |
Toxic effect of carbon monoxide |
8 |
1.7 |
8 |
0.3 |
7.49 |
2.74 |
20.46 |
993 |
Effects of air pressure |
11 |
2.3 |
46 |
1.6 |
2.05 |
1.01 |
4.17 |
TABLE G-5 Among All Service Members, Rates of Hospitalization for Specific Diagnoses and Adjusted Rate Ratios Comparing Hospitalization Rates Following at Least One Dose of AVA (“Post”) with Hospitalization Rates Before First AVA Dose (“Pre”), by Sex, U.S. Armed Forces, Active Duty, 1998 to 2000
|
ICD-9-CM Code(s) |
Description |
Anthrax Immunization Status |
Adjusted Rate Ratio |
95% Confidence Intervals |
||||
Post |
Pre |
||||||||
Number |
Rate per 100,000 |
Number |
Rate per 100,000 |
||||||
Both Sexes |
710-719 |
Arthropathies and related disorders |
1,543 |
209.0 |
7,674 |
227.8 |
0.88 |
0.83 |
0.93 |
493 |
Asthma |
94 |
12.7 |
629 |
18.7 |
0.63 |
0.51 |
0.79 |
|
710 |
Diffuse diseases of connective tissue |
9 |
1.2 |
61 |
1.8 |
0.86 |
0.42 |
1.78 |
|
250 |
Diabetes mellitus |
67 |
9.1 |
445 |
13.2 |
0.65 |
0.50 |
0.84 |
|
380-389 |
Diseases of the ear and mastoid process |
67 |
9.1 |
368 |
10.9 |
0.87 |
0.67 |
1.14 |
|
357 |
Inflammatory and toxic neuropathy |
13 |
1.8 |
89 |
2.6 |
0.75 |
0.41 |
1.35 |
|
427 |
Cardiac dysrhythmias |
170 |
23.0 |
998 |
29.6 |
0.77 |
0.65 |
0.91 |
|
200-208 |
Lymphosarcoma and reticulosarcoma |
43 |
5.8 |
311 |
9.2 |
0.70 |
0.51 |
0.97 |
|
340 |
Multiple sclerosis |
32 |
4.3 |
103 |
3.1 |
1.31 |
0.87 |
1.98 |
|
410 |
Acute myocardial infarction |
68 |
9.2 |
384 |
11.4 |
0.97 |
0.74 |
1.27 |
|
240-246 |
Disorders of thyroid gland |
48 |
6.5 |
334 |
9.9 |
0.76 |
0.56 |
1.04 |
|
530-537 |
Diseases of esophagus, stomach, and duodenum |
475 |
64.3 |
2,135 |
63.4 |
1.02 |
0.92 |
1.13 |