Escherichia coli O157:H7 in Ground Beef Review of a Draft Risk Assessment (2002) / Chapter Skim
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6 Risk Characterization
6 Risk Characterization
Pages 89-96
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From page 89... ...
DEFINITION OF KEY TERMS The chapter's definitions are clearly spelled out and helpful in interpreting the material. However, as mentioned elsewhere in this review, some of the draft report's definitions are not the standard ones used in the scientific literature or other quantitative risk assessments.
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From page 90... ...
However, it fails to capture the sense in which most risk analysts apply it: the systematic investigation of whether and to what extent changes in model inputs across a plausible range of values affect model outputs. The committee suggests that the final risk assessment adopt the more common definition of sensitivity analysis.
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From page 91... ...
In general, the committee suggests that where possible the final risk assessment adopt the definitions established by one of the major organizations that have already published glossaries and that alternative expressions be used in other circumstances. The World Health Organization (WHO, 1995)
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From page 92... ...
The committee recommends that the Risk Characterization chapter be refocused to concentrate on the analysis of severe illnesses associated with E cold 0157:H7 infection, the subpopulations known or thought to be most vulnerable to them, and the interventions that might have the greatest effect in preventing them.
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From page 93... ...
Risk of Illness for the US Population This subsection summarizes modeling results that are likely to be used often for public health decision-making, and it evaluates the overall risk of illness, given the population distribution of exposure and the doseresponse function. The risk characterization for the US population and, as noted above, selected vulnerable subpopulations should thus be the central output of the risk assessment.
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From page 94... ...
For clarity, the committee suggests that the X axes of Figures 5-1 and 5-2 labeled "Dose" be relabeled "Number of E cold 0157:H7 per Serving" to relate them more directly to the data and analysis summarized in Table 5-2 in the draft risk assessment.
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From page 95... ...
and home environments, and it points out that practices in the fastfood mass-retail establishments where a considerable proportion of ground-beef meals are prepared and consumed may differ from those of other HRI businesses. The draft risk assessment correctly notes this as a research need.
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From page 96... ...
Alternatively, the level of uncertainty in these conclusions needs to be much more forcefully stated. The committee believes that recommendations regarding the potential applications of the model's various outputs would be a useful addition to the final risk assessment.
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