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Appendix A: Agendas of Open Sessions of Committee Meetings
Pages 231-242

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From page 231...
... Appendixes
From page 232...
... Appendixes
From page 233...
... concerns regarding the threat of transmissible spongiform encephalopathies (TSEs) to their food and blood supplies · Clarify the study tasks and determine a strategy for accomplishing them · Determine if the committee is lacking any area of needed expertise · Determine the format and identify presenters who should be invited to address the committee at subsequent meetings · Determine study milestones and subsequent meeting dates 233
From page 234...
... Lunch 1:00 1:30 2:00 DOD stakeholder meeting summary COL Ken Bertram Break Protecting the DOD's food supply from TSEs COL Scott Severin, Deputy Director, DOD Veterinary Service Activity, Office of the Army Surgeon General Protecting the DOD's blood supply from TSEs CDR Rebecca Sparks, Deputy Director, Armed Services Blood Program Evidence for or against transmission of TSEs in blood Roger Y Dodd, Ph.D., committee member Surveillance of TSEs in animals and risks to human health in the United States Elizabeth S
From page 235...
... will: Review concepts of prion conversion, pathogenesis, and detection Review current and newer techniques useful for TSE diagnostics Discuss the compositions of the interim report and the final study Develop draft recommendations regarding the essential research that > lead to better TSE diagnostics > address animal models, bioassays, reagents, and the research infrastructure needed for TSE research > achieve critical breakthroughs to jump-start progress in prion-disease science
From page 236...
... Prusiner, M.D., consultant to the committee PrP conversion, mechanisms, pathogenesis, and future research needs Byron Caughey, Ph.D., Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, Montana 12:30 Mini-symposium: prion structure and structure-based detection · Too! 1: Electron crystallography Holger Wille, Ph.D., Institute for Neuro~legenerative Diseases, University of California, San Francisco 2:00 · Too!
From page 237...
... Extraneural pathogenesis of prion disease and research gaps Adriano Ag~zzi, M.D., Ph.D., consultant to the committee 9:30 PrPSc diagnostics; building research capacity; international collaboration Jean-Philippe Deslys, M.D., Ph.D., Head of the Prion Group, Medical Research Department, Commissariat ~ I'Energie Atomique, Fontenay-~ux-Roses, France 10:30 Adjourn Open Session Meeting 3 October 29-30, 2002 Arnold & Mabel Beckman Center of The National Academies Irvine, California Meeting Objectives · Review and discuss the critical study time lines and tasks · Review and refine draft interim report and recommendations · Receive briefings on Creutzfel~t-}akob disease (C}D) and chronic wasting disease (CWD)
From page 238...
... Department of Agriculture, Fort Collins, Colorado Break CWD surveillance of cervids from a state's perspective Sam D Hol~nd, D.V.M., South Dakota Animal Industry Board, Pierre, South Dakota Novel techniques at the cutting edge of protein detection Roger Brent, Ph.D., Associate Director of Research, The Molecular Sciences Institute Inc., Berkeley, California Adjourn open session Meeting 4 lanuary 21-22, 2003 500 5th Street, NW, Room 201, Washington, DC Meeting Objectives · Determine the content of the final report · Develop research recommendations for TSE surveillance and future research needs · Plan the program for the final meeting
From page 239...
... Anthony Williamson, Ph.D., Department of Immunology, The Scripps Research Institute, La bold, California 1:30 Gene therapy as a treatment for TSE Howard Federoff, M.D., Ph.D., Department of Neurology, University of Rochester School of Medicine, Rochester, New York 2:15 Break 2:30 Noninflammatory spongiform neurodegeneration caused by a conventional virus John L Portis, M.D., Rocky Mountain Laboratories, National Institutes of Health (NIAID)
From page 240...
... Johnson, M.D., Committee Chair Mini-Symposium: Controlling BSE 9:00 10:30 Control points in the beef processing industry Mr. Dave Harlan, Taylor Packing and Excel Food Solutions Company, Wyalusing, Pennsylvania The role of the federal government in managing and controlling the risk of BSE in the United States Linda Detwiler, D.V.M.; Veterinary Service, Animal and Pant Health Inspection Service, USDA, Robbinsville, New Jersey Break
From page 241...
... Thompson Hobbs, Ph.D.; Natural Resource Ecology Laboratory, Colorado State University, Fort Collins, Colorado 10:00 10:30 Break The quest for an FDA-approved test to screen human blood and blood products for priors: regulatory, scientific, and commercial obstacles Jay Epstein, M.D.; Director Office of Blood Research and Review, FDA, Rockville, Maryland and David M Asher, M.D., consultant to the committee
From page 242...
... 242 11:30 Lunch in room 101 12:30 p.m. Adjourn open session ADVANCING PRION SCIENCE


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