Guidelines for Human Embryonic Stem Cell Research (2005) / Chapter Skim
Currently Skimming:
Appendix A: Compilation of Recommendations
Appendix A: Compilation of Recommendations
Pages 123-130
The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.
From page 123... ...
The committee would also serve to review basic hES cell research using preexisting anonymous cell lines that does not require consideration by an Institutional Review Board. Recommendation 2: Through its Embryonic Stem Cell Research Oversight (ESCRO)
|
From page 124... ...
Research that is permissible after notification of the research institution's ESCRO committee and completion of the reviews mandated by current re quirements. Purely in vitro hES cell research with pre-existing coded or anony mous hES cell lines in general is permissible provided that notice of the re search, documentation of the provenance of the cell lines, and evidence of compliance with any required Institutional Review Board, Institutional Ani mal Care and Use Committee, Institutional Biosafety Committee, or other mandated reviews is provided to the ESCRO committee or other body desig nated by the investigator's institution.
|
From page 125... ...
RECOMMENDATIONS FROM CHAPTER 4 Recommendation 8: Regardless of the source of funding and the applicability of federal regulations, an Institutional Review Board or its equivalent should review the procurement of gametes, blastocysts, or somatic cells for the purpose of generating new hES cell lines, including the procurement of blastocysts in excess of clinical need from in vitro fertilization clinics, blastocysts made through in vitro fertilization specifically for research purposes, and oocytes, sperm, and somatic cells donated for development of hES cell lines derived through nuclear transfer. Recommendation 9: Institutional Review Boards may not waive the requirement for obtaining informed consent from any person whose somatic cells, gametes, or blastocysts are used in hES research.
|
From page 126... ...
RECOMMENDATIONS FROM CHAPTER 5 Recommendation 13: When donor gametes have been used in the in vitro fertilization process, result ing blastocysts may not be used for research without consent of all gamete donors. Recommendation 14: To facilitate autonomous choice, decisions related to the production of em bryos for infertility treatment should be free of the influence of investigators who propose to derive or use hES cells in research.
|
From page 127... ...
g. A statement that the hES cells and/or cell lines might be used in research involving genetic manipulation of the cells or the mixing of human and nonhuman cells in animal models.
|
From page 128... ...
. Recommendation 22: Institutions that are banking or plan to bank hES cell lines should establish uniform guidelines to ensure that donors of material give informed consent through a process approved by an Institutional Review Board, and that meticu lous records are maintained about all aspects of cell culture.
|
From page 129... ...
(v) A website that contains scientific descriptions and data related to the cell lines available.
|
From page 130... ...
(e) Clear criteria for distribution of cell lines, including but not limited to evidence of approval of the research by an Embryonic Stem Cell Research Oversight committee or equivalent body at the recipient institution.
|
Key Terms
This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
More
information on Chapter Skim is available.