Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations Initial Report (2008) / Chapter Skim
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4 Summary of the Effects of Combined Exposure to Carbon Monoxide and Hydrogen Cyanide and Recommendation for Combined-Exposure Risk Assessment
4 Summary of the Effects of Combined Exposure to Carbon Monoxide and Hydrogen Cyanide and Recommendation for Combined-Exposure Risk Assessment
Pages 11-12
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From page 11... ...
The present assessment of the toxicity of CO + HCN co-exposures could provide a guideline to the Army for evaluating the hazard of exposures in a confined environment and implementing mitigation procedures. CO and HCN are two of the toxic gases of major concern produced in fires and other combustion events (Esposito and Alarie 1988, Sanders et al.
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From page 12... ...
However, additive lethal effects might not have been detected because of the great variation in the data points; the large confidence limits may have prevented detection of the combined biological effects of CO + HCN. Moore's group concluded that the combined lethal effects in CO-exposed mice given lethal doses of cyanide salt by intraperitoneal injection were synergistic (Norris et al.
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