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Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations Initial Report (2008) / Chapter Skim
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7 Conclusions and Recommendations
Pages 18-19

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From page 18...
... and more subtle effects such as decrements in performance of the tank crew. While a theoretical case could be made perhaps for a less than additive effect based on, for example, changes in respiration and gas uptake, the committee believes that it is prudent to expect that the additive effect of the combined exposure observed with high concentrations would occur if subjects were exposed to low concentrations (less than 4 ppm for HCN and concentrations of CO producing carboxyhemoglobin [COHb]
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From page 19...
... Since the spikes observed in air levels of CO within the tank during firing scenarios were of such short duration taking into account respiratory rate and tidal volume, the committee concluded that it was not overly concerned about them in comparison with longer, possibly increasing, COHb levels. However, because of conditions where ambient CO concentrations are changing rapidly, it is recommended that the use of CFK equation to calculate COHb levels needs to be verified with blood COHb measurements.
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Key Terms

  • hazard quotient
  • blood levels
  • cohb levels
  • quotient approach
  • air levels

  • blood level
  • firing scenarios
  • additive effect
  • blood cohb
  • cyanide makes

  • handling blood
  • adverse blood
  • influence cyanide
  • determining cyanide
  • blood samples

  • duration taking
  • short duration
  • technical difficulties
  • levels difficult
  • cfk model

  • human exposure
  • producing carboxyhemoglobin
  • respiratory rate
  • defining adverse
  • biological monitoring

  • address subtle
  • add substantially
  • possibly increasing
  • military documents
  • correlated exposures


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