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Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations Final Report (2008) / Chapter Skim
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5 Is There Dose-Related Performance Degradation Resulting from Combined Exposures to Carbon Monoxide and Hydrogen Cyanide?
Pages 18-19

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From page 18...
... In addition, the assessment is complicated by the presence of other combustion products released both from weapons firing and from combusting vehicle fuel, and the committee recognizes that the potential hazardous effects of these other products, especially in combination with CO and HCN, may also be important. Hence, although the committee still considers the hazard quotient approach to risk assessment valid, and it reiterates its recommendation that the approach be used until further findings suggest otherwise, the committee concludes that additional information is needed to better understand possible synergisms between CO, HCN, and other combustion products that could help refine this risk assessment.
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From page 19...
... An alternative would be to design neurobehavioral experiments in nonhuman primates to test the effect of HCN in combination with CO. An additional or alternative approach considered viable by the committee is to conduct field studies in actual armored vehicles, where CO and HCN would be measured simultaneously along with crew performance (for example, reaction times)
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Key Terms

  • crew performance
  • combustion products
  • reaction times
  • help refine
  • suggest otherwise

  • conduct field
  • carbon monoxide
  • multiple uncontrollable
  • independent body
  • potential hazardous

  • directly assist
  • studies specifically
  • field experiments
  • affect crew
  • require additional

  • considered viable
  • quotient approach
  • actual armored
  • combined exposure
  • hazardous effects

  • approach considered
  • literature suggests
  • findings suggest
  • hcn combined
  • experimental results

  • neurobehavioral effects
  • act individually
  • exposure concentrations
  • combusting vehicle
  • additional chemicals


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