Continuing Assistance to the National Institutes of Health on Preparation of Additional Risk Assessments for the Boston University NEIDL, Phase 3 (2011) / Chapter Skim
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Letter Report
Letter Report
Pages 1-13
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, Boston University2 to provide you and your Blue Ribbon Panel with further technical input on the scope and design of any additional studies that may be needed to assess the risks associated with the siting and operation of the NEIDL. In particular, you asked the NRC Committee to meet with the NIH Blue Ribbon Panel in public at key milestones in the development of the draft risk assessment.
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Ahearne, Chair Committee on Continuing Assistance to the National Institutes of Health on Preparation of Additional Risk Assessments for the Boston University NEIDL cc: Amy Patterson, M.D.
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Haas, Drexel University, Philadelphia, PA Marc Lipsitch, Harvard University School of Public Health, Boston, MA Stephen Ostroff, Pennsylvania Department of Health, Harrisburg, PA Catherine Wilhelmsen, U.S. Army Medical Research Institute for Infectious Diseases, Frederick, MD Although the reviewers listed above have provided many constructive comments and suggestions, they were not asked to endorse the conclusions or recommendations, nor did they see the final draft of the report before its release.
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Technical Input on the National Institutes of Health's Draft Supplemental Risk Assessments and Site Suitability Analyses for the National Emerging Infectious Diseases Laboratory, Boston University: A Letter Report (2007)
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-- Are the uses of the hybrid branching-compart ment models and the extreme values analysis sound? 4 Technical Input on Any Additional Studies to Assess Risk Associated with Operation of the National Emerging Infectious Diseases Laboratory, Boston University: A Letter Report (2008)
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This letter report contains the NRC Co mmittee's written comments in response to that November 2 meeting. Statement of Task for This Letter Report As with the Committee's previous two letter report of the same title, the statement of task for this letter report is as follows: The NIH will engage the Committee on Technical Input on the NIH's DSRASSA for the Boston University NEIDL at key milestones during the development of a 5 Continuing Assistance to the National Institutes of Health on Preparation of Additional Risk Assessments for the Boston University NEIDL, Phase 1: A Letter Report (2010)
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Documents reviewed and discussed at these meetings will be made available to the public. Following each meeting with the BRP, the NRC Committee in closed session will prepare brief letter reports on the preliminary results of the supplementary risk analyses, focusing on whether the analyses are scientifically and technically sound in general and whether they address the public health concerns previously raised by the NRC in its review of the July 2007 DSRASSA.
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It might be helpful to craft a paragraph for this chapter describing how environmental justice seeks to compare population characteristics, not just density. Other differences in environmental justice communities might include variations in host population susceptibilities to infectious agents and access to appropriate health care.
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Chapter 4 and Appendices D, E, and F: Event Sequence Analysis This chapter contains numerous tables of information about event and exposure scenarios. However, because the basis for assigning frequencies to the various exposure categories (e.g., Table 4-5 on pp.
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Third, the assignment of frequency category C (1 in 10,000 to 1 million years) to the high consequence earthquake scenario, given the paucity of actual data on occurrences of large magnitude quakes on the eastern seaboard of the US, is a concern.
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workforce risk for needle stick. It appears that the risk of a needle stick event should go up with number of workers and perhaps with numbers of injections required.
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Chapter 10 and Appendix M: Environmental Justice The Committee believes that the RA team has made substantial progress in addressing environmental justice and Chapter 10 and Appendix M set out a credible and thoughtful approach to environmental justice based largely on federal and state environmental justice executive orders and policies. There is still, however, one significant short-coming in the environmental justice analysis, which is captured in lines 23 to 26 on page 10-22.
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It is clear that NIH and the Blue Ribbon Panel have gone to unprecedented lengths to improve the risk assessment for the NIEDL and have made substantial advances. It is the Committee's hope that the comments in this letter report will be taken as suggestions for improving the final draft report further.
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