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Panel VII: Biomedical Growth Opportunities
Pages 107-116

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From page 107...
... "In 2001, our health care leadership and civic leadership came together and established the goal of making northeast Ohio a nationally recognized center for health care innovation. Those leaders recognized that this could not be the role of any single institution, but had to be a collective commitment, including investments in translational research capabilities, the identification of capital sources, and supportive state policy in the form of the Third Frontier program.
From page 108...
... BIOMEDICAL RESEARCH AND THE HEALTH CARE INDUSTRY Frank Douglas Austen BioInnovation Institute in Akron Dr. Douglas acknowledged at the outset that "this is actually a very broad and difficult topic," so that instead of trying to cover all its aspects, he would focus on one movement that has "everything to do with biomedical research and everything to do with how we manage our health." That movement has been called "personalized health," and includes a greater emphasis on prediction and prevention.
From page 109...
... Moving Closer to Personalized Medicine Dr. Douglas suggested that other fundamental changes in biomedical research and health care could make the field more predictive and move it closer to personalized medicine.
From page 110...
... He reiterated some of the major points of the "Personalized Health Manifesto," asserting that "a reordering of priorities is required to stress the application and translation of what has been learned to improve health and to reduce health care costs. If you think about these kinds of changes in a major industry," he concluded, "I think you begin to see tremendous opportunities for innovation and job creation." BRINGING MEDICAL INNOVATIONS TO MARKET Delos "Toby" Cosgrove Cleveland Clinic Dr.
From page 111...
... Morgenthaler thought they would find potential new companies only based on medical devices. While it is true that only a single diagnostic company had been formed, the Cleveland Heart, more healthcare IT companies are appearing as younger physicians generate new ideas in this field.
From page 112...
... It would focus on identifying the particular genomic changes of each person -- either genetic changes inherited from parents or somatic changes acquired after birth. "The genes begin to be the basis for how we actually diagnose, treat, and ultimately prevent disease.
From page 113...
... Barker said, the human genome has now been sequenced, and that has given scientists the tools they need to sequence cancer genomes. "Francis Collins and I started a program called the Cancer Genome Atlas," she said, "and that's one of the places we had to start with personalized medicine.
From page 114...
... Barker said that creating a system of personalized cancer medicine will require the IT infrastructure, a system of handling biospecimens, a compendium of all the genomic changes, and a responsive translational research infrastructure. All this will require new funding.
From page 115...
... Cosgrove said he would second that, and that the Cleveland Clinic had "tried to take a fairly aggressive policy, where all our physicians list all their financial relationships and make them public on the Internet. I think that's the first and a very reasonable step to take." Robert Schmidt, of Cleveland Medical Devices, asked about some major medical trends, including the Internet and miniaturization.
From page 116...
... Michael Milken has suggested that he will fund research around prostate cancer if in fact results are shared openly and immediately. That's a huge step in the right direction.


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