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Factors Important for the Selection of Key Patient Management Issues and Related Research Activities
Pages 25-28

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From page 25...
... The multiple patterns of treatment for young and elderly AMI patients include many high-cost and high-risk procedures, with little clear relation between specific therapies and long-term outcome, particularly functional health status and psychological aspects. SELECTING PATIENT MANAGEMENT ISSUES Several factors affect the selection of key patient management issues for AMI in elderly patients.
From page 26...
... SELECTING RESEARCH TOPICS AND ACTIVITIES Content, Conduct, and Use of Research In specifying research activities focused on high-priority AMI topics, the committee raised three additional points concerning the content, conduct, and use of this research. First, it endorsed four generic areas of concern identified at the 1988 clinical workshop to set priorities for the Effectiveness Initiative: (1)
From page 27...
... Third, studies on specific illnesses serve as prototypes for examining other, similar conditions. For instance, studies of primary and secondary prevention, early diagnosis and treatment, staging of acute disease in relation to outcome, treatment options, and quality-of-life outcome measures related to AMI provide opportunities to address conceptual and methodologic issues for other illnesses that are prevalent in the Medicare population, that have both acute and chronic aspects, or that affect the cardiovascular system.
From page 28...
... Some committee members raised concern about the accuracy of such records, the value of retrospective abstracting rather than concurrent analysis, and the lack of clinical peer review of both the data set itself and the PRO methodology. These difficulties were particularly emphasized with regard to risk stratification methodologies and identification of the sequence of diagnostic and therapeutic events.


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