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Report of the Committee on Mapping and Sequencing the Human Genome (1988) / Chapter Skim
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APPENDIX A: Glossary
Pages 96-97

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From page 96...
... Codon -- The nucleotide triplet in messenger RNA that specifies the amino acid to be inserted in a specific position in the forming polypeptide during translation. Cosmid -- Plasmid vectors designed for cloning large fragments of eukaryotic DNA.
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From page 97...
... For example, restriction endonuclease mapping of human structural genes for beta hemoglobin chains has shown that parents with the sickle cell mutation produce abnormal restriction fragments. Reverse transcription -- DNA synthesis from an RNA template, mediated by reverse transcriptase.
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Key Terms

  • specific position
  • rna template
  • molecular weight
  • reverse transcriptase
  • random coil

  • produce abnormal
  • messenger rna
  • disulfide bonds
  • sodium dodecyl
  • binary fission

  • beta hemoglobin
  • anionic detergent
  • structural genes
  • ribonucleotide triplet
  • dna polymerase

  • restriction fragments
  • molecules assume
  • forming polypeptide
  • coil follows
  • protein chain

  • classical sense
  • linear sequence
  • allelic forms
  • specific endonuclease
  • gel electrophoresis

  • entire set
  • restriction fragment
  • threadlike structures
  • ancestral cell
  • codons specifying


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