Biotechnology in China (1989) / Chapter Skim
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7Research Highlights During the course of the literature survey, it became apparent that certain research in China has progressed to an international level. The following section describes the most promising of these projects in both basic and applied biotechnology.
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possible to determine the structure of a variety of peptides and proteins by direct means. This would have broad and important implications for protein engineering.
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1976, an American group found that certain strains of CMV carry a small RNA, termed satellite RNA, in addition to the four major genomic species. Satellite RNA, which is completely dependent on its helper virus for replication, bears no nucleotide sequence homology to CMV but can interfere with its replication and ability to cause disease symptoms.
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that these plants are resistant in inoculated as well as systemically infected leaves. This might reflect a difference between the replication of the monomer satellite cDNA insert used by Tien as compared with the dimer insert used by Baulcombe.
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high risk for chronic liver disease and hepatocarcinoma. A notable characteristic of HBV is that it can be transmitted before or at birth from infected mother to baby.
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the Beijing Institute of Virology is attempting to develop a more practical vaccine based on live vaccinia virus recombinants. Toward this end, the HBsAg gene was linked to a strong viral promoter and then inserted into the Tian Tan strain of vaccinia virus; this is a vaccine strain that has been used extensively for the eradication of smallpox in China.
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Tsao, H., Ren G.F., and Chu, C.M., "Gene Coding for the Late 11,000-Dalton Polypeptide of the Tian Tan Strain of Vaccinia Virus and Its 5'-Flanking Region: Nucleotide Sequence," Journal of Virology 57 (1986)
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Ouyang, J.W., He, D.G., Feng, G.H., and Jia, S.E, "The Response of Anther Culture to Culture Temperature Varies with Growth Conditions of Anther-Down Plants, Plant Science 49 (1987)
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