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Issues in Risk Assessment (1993) / Chapter Skim
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5.2 Correlation Between q1* and the TD50
Pages 136-138

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From page 136...
... The strong negative association between the MDT and linearized upper bounds on the slope of the dose-response curve in the low dose region is demonstrated empirically in Figure 4 using the 191 carcinogens considered previously in section 3.1. Upper bounds based on both the multistage model and model-free extrapolation are highly correlated with the MDT, with Pearson correlation coefficients of -0.941 and -0.960 respectively.
From page 137...
... Please use the print version of this publication as the authoritative version for attribution.APPENDIX F FIGURE 4a Association between upper bounds on low dose slope and maximum tolerated dose.
From page 138...
... Please use the print version of this publication as the authoritative version for attribution.APPENDIX F FIGURE 4b Association between upper bounds on low dose slope and maximum tolerated dose.


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