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Issues in Risk Assessment (1993) / Chapter Skim
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Pages 53-53

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From page 53...
... The fourth option would use MTD testing as part of an overall testing strategy that separates carcinogens from noncarcinogens and provides information useful for determining human relevance; this could take one of two forms -- a two-track system that comprises full testing and limited testing and a system of sequential studies. These options are presented below and are followed by discussions of their advantages and disadvantages.
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Key Terms

  • screening studies
  • lower doses
  • effects expected
  • separates carcinogens
  • information useful

  • overall testing
  • determining human
  • options relative
  • options considered
  • continue carcinogenicity

  • initially proposed
  • physiologic effects
  • status quo
  • dose dependence
  • mtd workshop

  • workshop organized
  • testing strategy
  • alter carcinogenic
  • human relevance
  • limited testing

  • dose according
  • provides information
  • mtd testing
  • fourth option
  • committee considered

  • authoritative version
  • carcinogenic response
  • print version
  • federal liaison
  • arbitrary fraction


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