Issues in Risk Assessment (1993) / Chapter Skim
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Executive Summary
Executive Summary
Pages 1-2
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. Mantel and Bryan published in 1961 the first paper on estimation of low dose risk based on data obtained from tests in which animals were exposed at high doses; formal procedures for performing animal bioassays, which are critically important for gathering information for risk assessment, had been standardized only in the 1960s and 1970s; and formal risk assessment began to be conducted regularly in the late 1970s.
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The committee has focused on methodology; accordingly, its deliberations on each topic takes into account not only potential problems with existing methods, but also the suitability of alternative methods for risk assessment. The committee consulted closely with federal agencies whose mission is to make decisions based on risk assessment of environmental and human health hazards.
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