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Calculating the Secrets of Life Contributions of the Mathematical Sciences to Molecular Biology (1995) / Chapter Skim
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Pages 18-21

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From page 18...
... THE HUMAN GENOME PROJECT With the identification of the CF gene as well as a number of other successes, it has become clear that molecular genetics has developed a powerful general paradigm that can be applied to many inherited diseases and will have a profound impact on our understancling of human health. Unfortunately, the paradigm involves many tedious laboratory steps: genetic mapping (finding a polymorphism closely linked to the
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From page 19...
... Physical maps. The goal is to produce a collection of overlapping pieces of DNA that cover all the human chromosomes.
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From page 20...
... ~ ~ ~ :< ¢ ~ X ~ Y Z En S X ~ id: Cal ~ LO Cd ~ Cd ~ ~ ~ to Ct En ~ if: ~ ~ En E" in A)
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Key Terms

  • physical map
  • genetic mapping
  • disease gene
  • dna sequence
  • human chromosome

  • genome project


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