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Appendix C: Summary of Medically Assisted Conception: An Agenda for Research
Pages 78-100

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From page 78...
... In contrast, there has been progress in maturing oocytes in culture and in analyzing genetic abnormalities in early embryos. It is hoped that the inclusion of this summary will help to deepen the readers' appreciation of issues, from both the science and the public policy arenas, that still confront the fields of fetal research and fetal tissue transplantation.
From page 79...
... APPENDIX C 79 MEDICALLY ASSISTED CONCEPTION An Agenda for Research Report of a Study by a Committee of the INSTITUTE OF MEDICINE Division of Health Sciences Policy NATIONAL RESEARCH COUNCIL Board on Agriculture National Academy Press Washington D.C.
From page 80...
... 80 FETAL RESEARCH AND APPLICATIONS NOTICE: The project that is the subject of this report was approved by the Governing Board of the National R£ search Council, whose members are drawn from the councils of the National Academy of Sciences the N~;mn=1 Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special cc mpetencies and with regard for appropriate balance.
From page 81...
... APPENDIX C Ih~ll~ OF MEDICINE N=ICt~L REM CANCEL =1 A=iallture M}1~ Ct]
From page 82...
... 82 FETAL RESEARCH AND APPLICATIONS J~9PN UP Proffer of Molecular, Cellular, arm Devel~ntal Biology, D - arty of Pulsar, Cellular arx] Developmental Biology, University of C~lor~o at ~~1d~' ~~1d~' ~lo~o EDWARD E
From page 83...
... ADVANCED IN 1~ ~AC1ICE AND SCIONS BP~ OF MEDICALLY ASSIST OXlCEPl~ON ....... Devel~znents in Han In Vitro Fertilization Devel~nts in Assisted ~tian in Food-~ucing Animals Gametogenesis and Gametes .
From page 84...
... Ryan chat In Committee on the Basic Science Notions of Medically Assisted Conception
From page 85...
... In 1986, the Icons Board an Health Sciences Polity Awakened a Retire of experts in the fields of Man are anew reseat, clinical practice, law, ethics, am public policy to consider ~ of me iamb rats" at the earlier Satin. This group was awed to advise the IS An Mar it Behold pursue a stay in arty of the areas in chide difficult ~=~^= had been rams by the practice of epically assisted ~tia~n~ly, p~f~=ional, social, led, are ethical imps, On Gentian to q~estic~ns of science policy.
From page 86...
... 86 FETAL RESEARCH AND APPLICATIONS A:L~a~h Me craw to Me remittee ire: - es acasideraticm of ways of lc~erir~ barriers to progress in regear=, ~ of Rich are calmed by 1~3a1 and ethical Urns, the cites was not cx~titut~ to resolve or make rattan ~ ~ A: - C Other, it was to aa~f~ne i+= deliberation to amsideraticn of ways Mat scientists might ~ihite to the f~ of the Mate ~1~1 arm ethical imps Dam.
From page 87...
... Social ~TIE; that On be A~IZ~ by IVIES P`esear~ did at p~hi~ forward the fliers of medically assisted Option has the potential to provide benefits ~ the limited numbs of couples whose infertility may be solved by IVFEr. Here are expectations that sup research weld Cable practiti~s to identify genetic defects in embryos without damager thy, arm to detain He of Oryx without desire thy, so that thme with ~-li~1 Optic i~= can be identified at a veer early stage.
From page 88...
... 88 FETAL RESEARCH AND APPLICATIONS o Infertility. Me ~~~ of the problem of Man infertility is reflected By the lair of Woo with Midair faith' —4.4 million or 8.2 percent of Woo of ~il,~'ir~ age in 1982 (National Ouster for Health Statics;, 1985)
From page 89...
... Barriers to Progress in In Vitro Fertilization and Embryo Transfer Since the birth of Louise Brown in England ~ 1978, in vitro fertilization with embryo replacement has beoare an estate' inched method of trea~t for certain type of infertility that do not z~ to alternative methods of treatment. However, the Dances of Marc in IVF are relatively leer.
From page 90...
... So Bit am Social To FETAL RESEARCH AND APPLICATIONS He of fix ethical ar ~ ~ imps that arise few the variates forms of Heisted gentian are unrelated to decisions gut He prongs of regear=. Temples of these are Bestirs abate the pr~c~ of tax rights of ganete Is, gestating prize, arm social parents; the Hip of cryapr~ "bryc6; arm Be sale of gags ~ "Bryan.
From page 91...
... APPENDIX C 91 }in glens (P.L.
From page 92...
... 92 FETAL RESEARCH AND APPLICATIONS Otter rewriting at least 25 Gantries. Our Australian Matte fat research An early (pre~lar~tatia~)
From page 93...
... APPENDIX C ax~niG~tic~n to allow crcss-fertil~ticm of ~^= and de~cQ~ of Loire relati~hi}e a~q initiators ~rq similar AL to Exiles. Say of Pesear~ Material for Exits with Emmy and 0 Pr~t~ ye ~ttee's Imp provided May It examples of Is in which inf~tia~ it r—motive E~?
From page 94...
... 94 FETAL RESEARCH AND APPLICATIONS o ~rminaticn of the mole of parasite factors incl~ir~ fi~last growth fact=, Italic C, It growth factor, arm int~l~1 Cal the deviant use diffe~itiaticn of He ga - sates. O Sty analyst to identify no arm a~orm~1 Berm ~ the devel~nt of maracas for at Berm.
From page 95...
... APPENDIX C 0 entire investigation to identify the genes for zeta proteins in Bats ties, eppeci Al ly hands. O Fir delineation of the role of zcna protein, especially ZP2 ZP3, in Sperm brim.
From page 96...
... 96 FETAL RESEARCH AND APPLICATIONS o Definition of the fat released by mb~ that He curio charges at the site of ~lar~ati~. O I~tificaticm of the role of embryo rel^~ factors ill ressir~g the Abbe respcmses of the Our.
From page 97...
... APPENDIX ~ Devel~ir~ PI Policy C=x:lusicms arm Re~ti~s "dk of a onanism for ~1 ire with ethical dis~fc aver Me use of Frye in r~ has Bleed the rate of progress in resort by, in effect, placid a ~ratarium cm the use of federal foes far eight years. this has h" ur~esir~le results: the Inn clinical practice of INFER is less effective than it might have been had research pi at a fasts pace; other McNally desirable Ills ~ as i~prwed ~a~, }I ~~ ~ pave e~a~ Dies, arm mare Ate effective Is of pr=3uc~ fop have dell at a pace ulcer than A
From page 98...
... 98 Basic Science F~urx3aticns FE TAL R E S EAR CH AND A PPLICA TIONS the Or and Urge of twin; i":l,~d in the research Ma indicate the exciting E~Ttia1 for Five scientific explo~ti~. He Settee believes that Metal research to embark the basic scions fanatics of drive biology Old be Intimated ark al.
From page 99...
... APPENDIX C ices to do with the a~anizatia, of clinics; arm the ads of Ed;, the are; to Did weed Able E~citia~s to Talc Are effectively, arx] polity mixes to make decisicas Al the basis of me best available inf~ticn.
From page 100...
... 100 FETAL RESEARCH AND APPLICATIONS REFIX African Collie of Ctstetrici~ arm Eulogists.


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