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Vaccine Safety Forum Summaries of Two Workshops (1997) / Chapter Skim
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GENETIC FACTORS AFFECTING DEVELOPMENT OF AUTOIMMUNITY
Pages 35-36

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From page 35...
... can also interact with genetic factors. Environmental agents that have been implicated in some autoimmune diseases include infectious organisms, foods, dietary supplements, drugs, toxic agents and other substances, occupational exposures, foreign cells, and medical devices.
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From page 36...
... The possibility that ERVs can be part of the disease process, as in the previously mentioned mouse model, has prompted one workshop speaker to consider the possibility that HERVs play a role in certain human diseases or in adverse events following vaccination. Because HERVs have the enzyme needed to copy and incorporate viral genetic material into human DNA, HERVs theoretically might copy and incorporate the viral genetic material presented in vaccines or natural infections (Urnovitz et al., 1996~.
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Key Terms

  • genetic factors
  • increased risk
  • viral genetic
  • hla subtype
  • genetic material

  • hervs theoretically
  • mhc genes
  • disease process
  • expression include
  • antigen processing

  • diseases include
  • human leukocyte
  • environmental triggers
  • medical devices
  • destroying condition

  • genetic marker
  • include hormones
  • factors acting
  • documenting genetic
  • natural infections

  • workshop speaker
  • human dna
  • human diseases
  • developing autoimmune
  • drug hydralazine

  • genetic risk
  • mhc molecules
  • herv expression
  • compounds generated
  • mentioned mouse


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