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Technical Assessment of the Man-in-Simulant Test Program (1997) / Chapter Skim
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Executive Summary
Pages 1-6

The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.


From page 1...
... to conduct research, clevelop anct procure support systems, and design equipment to protect U.S. military personnel from the increasing threat by foreign entities anct terrorist organizations to use chemical anct biological weapons.
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From page 2...
... review the test methodology for employing passive and active vapor and aerosol samplers during simulant tests at Dug~vay Proving Ground, Utah, and assess the plan for data collection and analysis 4. determine whether the current chemical simulant, methyl salicylate, or an alternative simulant should be used in the MIST program To accomplish this task the CSC established a panel of experts from members of the committee to undertake the MIST review.
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From page 3...
... is an innovative approach that takes into account regional variations in skin sensitivity to chemical agents. Although the basic approach is sound, the committee has the following reservations: A direct relationship has not been establishect between cholinesterase depression anct the percutaneous absorption of agent.
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From page 4...
... Recommendation 2a. The Army should measure regional variations in skin penetration for HO, VX, and simulant vapors using excised human skin harvested from various anatomic sites.
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From page 5...
... In acictition, concentrations inside the suit could be monitorect with either active or passive samplers, despite their logistical problems. Comparing simulant levels in the passive sampler with samples recovered from the stratum corneum of test subjects (the outermost layer of the skin, which can be removed by repeated applications of adhesive tape)
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From page 6...
... Modeling chemical protective ensembles is a ciaunt ing task, anct the Army's efforts to clevelop the MIST/BRHA should be commenclect. Modeling anct simulation technologies are invaluable tools for training for operations in a chemical anct biological warfare environment.
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Key Terms

  • protective ensembles
  • biological defense
  • chemical protective
  • methyl salicylate
  • human skin

  • test methodology
  • test program
  • excised human
  • alternative simulant
  • mist program

  • aerosol samplers
  • chemical agent
  • simulant tests
  • chemical simulant
  • employing passive

  • current chemical
  • test subjects
  • using methyl
  • active vapor
  • protection factors

  • chemical protection
  • biological agents
  • defense strategy
  • using excised
  • appropriate simulant

  • active samplers
  • regional variations
  • collective filtration
  • chemical agents
  • vitro studies


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