(NAS Colloquium) Neuroimaging of Human Brain Function (1998) / Chapter Skim
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Event-related functional MRI: Past, present, and future
Event-related functional MRI: Past, present, and future
Pages 11-18
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From page 11... ...
However, perhaps none of these methods has done more 10 ague the community of ~ems4~1 ncu~~ionti~s, Connie tag p~choIo~ist~ and clinicians as Abe development over tbc last hal~dec~de of ~nclionsl brain imaging using Relic {2sonance.FuncdonalbiRI(~) Rl~combinesat once thighs spatial resolution anatomic impair cap~1Ut~ ~ co~Tonal YR1 Cab the b~mo~namI speciEcib of nuclear tracer tecb~iqucs (positron emission Trap ~~in~ spatially accurate mapping of human brain Unison 10 underlying analog.
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From page 13... ...
shamed abut visualsti~ul~tion ssbrlefas34 msecin duration coUd elicit smalt but cleave detectable. signal changes (see Iig.
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From page 14... ...
wberc~s ~ctivi~ dustbin posterior visualaroas Ads flat Another notable ample of evenl-related TORI comes fro work of McL~rlhY Had co~llea~ues:~t Ya~.\lcC~rtl] Y~r ~39jexplorcdhowi/Tequentt~ ~ 1cv~nts',eprocessc~by tbobrain.lboypresenled continuous strings ofcharactcrs~i1b a tar~cts1hn~ appearing unpredictably once ovary 20 or so thals-a procedure that can be accomplished nnK within random interm~od trial designs Abe paradigm yields tbc E-documented P300 Ruben oxa~dn~d Huh evoked response potontiaLE~plorlng this cOtcl~ilEb/RIbyaver'~ingd~1sin r~lationtotbc onsets ofthain~equenl~vents de ~ nslratod preRontaland pariet~lact~ation perb~psconlributin~ 10.
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From page 15... ...
ALhou~b such a d~nstFaJon does not undermine the u1~by of Berating across cv~nt-rol~1ed TORI Dials as is simbarl~ done in nearly all behavioral and cooked response ~pot~nli,1 studies, ~ does provide confidence that (~n~l~o-~3is~ char~cter~tics of event-related procedures are quite good and that correlation of beb~io~al responses wish ind~id~1 trial R1 sisals sbonld be possible. Thus, garaging across that ~iU ~1~ ~ central finds in He modal hemp (amE response to be Observed, Berms e~mina~on of 1ndividu~1 b~mo~n~mic responses Any provide information about the unique aspects of an isolated ovens.
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From page 16... ...
A~11b~0~ug~h decays off ~ ~~ seconds are observed in Abe ppsL~ sigh cb-~cs on BOW Id arterial spin labeling Flu p~p~rl-ments, and u~p~rd of 1 sea far p<~:>t~nti:~] negative ~ Weal cb-^s {9~ the Stud bible temporal resolutionJs determined It by these dwells.
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From page 17... ...
Socond, nc~ and more s~phislicaled data analog methods oar greater understanding Of our d~a~ Rue sense and spcc~ Id we condom to impr~o our ability to address increasingly sophisdcatcd bypothescs Rout the underwing mecb~nisms of brain action Ibus 1bere is every reason to expect that the not balEdecsde of acuity in tab geld ~1 sub Wrath at least as ash as the last and caky us into nag domains of appeal and temporal resolution in our earls ~1 bumps brain mapping. We tank our many Porous al the Nucl/~ ~~n~bc Resonance Con tar, ~assacT:us~tls Oercr~1 l~l<>spilal far discussible and Suppers.
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From page 18... ...
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