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2 GUIDELINES FOR 3-QUINUCLIDINYL BENZILATE
Pages 15-18

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From page 15...
... At high doses, it has pronounced hallucinogenic effects. BZ was produced in the United States between 1962 and 1964, but production was terminated because of Me realization that BZ's effects on front-line troops could be varied and unpredictable (thus the term "buzz" or Agent BZ)
From page 16...
... With increased doses, there is increased heart rate, impaired performance, prostration, convulsion, and death rate. In a 42-day exposure of does administered BZ intravenously at 100 ~g/kg, slight gastrointestinal tract ~u~cera~on and bloody stools In auto or the exposed dogs and 25 % of the controls.
From page 17...
... It was the opinion of all medical and nursing personnel who supervised the four subjects that at no time during or after the study were there any additional signs or symptoms beyond the usual BZ effects. At the termination of the study, the subjects had certain mild medical conditions that might or might not have been related to BZ administration.
From page 18...
... The Army's field drinking-water standards for BZ are based on human studies. The criterion set by the Army Medical Department assumes water consumption ranging from 5 to 15 L/day, depending on climatic conditions.


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