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Toxicity of Military Smokes and Obscurants Volume 3 (1999) / Chapter Skim
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Appendix B: Vat Yellow 4
Pages 55-57

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From page 55...
... TOXICOKINETICS No studies have been conducted on the toxicokinetics of vat yellow 4. TOXICITY SUMMARY Effects in Humans There have been no reports of humans exposed either accidentally or in controlled laboratory environments to vat yellow 4.
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From page 56...
... Application of the paste to intact and abraded skin of rabbits produced no grossly discernible skin damage, and the acute dermal LDso for rabbits was greater than 4.6 g/kg of body weight. Instillation of the paste into the eyes of rabbits produced minimal reversible ocular irritation.
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From page 57...
... U.S. Army Medical Bioengineering Research and Development Laboratory, Fort Detrick, Frederick, MD.
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Key Terms

  • cancer institute
  • acute oral
  • rabbits produced
  • report vat
  • dermal toxicity

  • carcinogenic potential
  • dermal routes
  • animal studies
  • subcutaneous injection
  • female rats

  • cancer bioassay
  • minimal reversible
  • mice fed
  • reversible ocular
  • mice administered

  • toxicity tests
  • fort detrick
  • male mice
  • lethal dose
  • produced minimal

  • test animals
  • prolonged periods
  • medical bioengineering
  • ames mutagenicity
  • rats administered

  • thymidine kinase
  • commercial product
  • mouse lymphoma
  • kinase locus
  • standard cancer


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