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Submarine Exposure Guidance Levels for Selected Hydrofluorocarbons HFC-236fa, HFC-23,and HFC-404a (2000) / Chapter Skim
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Pages 20-20

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... At 20,000 and 50,000 ppm, there were significant dose-related decreases in maternal body-weight gain over the first 2 days of inhalation exposures. At 50,000 ppm, that was accompanied by significant reduction in food consumption and diminished alerting responses during the inhalation exposures.
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Key Terms

  • maternal toxicity
  • toxicity studies
  • developmental toxicity
  • alerting response
  • inhalation exposure

  • pregnant rats
  • body weight
  • alerting responses
  • food consumption
  • skeletal abnormalities

  • exposure concentrations
  • reproductive toxicity
  • diminished alerting
  • subchronic exposure
  • rats following

  • exposure concentration


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