Skip to main content

Submarine Exposure Guidance Levels for Selected Hydrofluorocarbons HFC-236fa, HFC-23,and HFC-404a (2000) / Chapter Skim
Currently Skimming:


Pages 22-24

The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.


From page 22...
... Acute and subchronic inhalation studies in rats have shown HFC-236fa to be of low toxicity. The principal effects of HFC-236fa appear to be attenuation of alerting response, narcosis, and cardiac sensitization.
Read the entire page →
From page 24...
... Submarine Exposure Guidance Levels for HFC-236fa Exposure Level NRC's Calculated Values Navy's Proposed Values 10,000 ppm 2,000 ppm 350 ppm 2,000 ppm 1,000 ppm 100 ppm The subcommittee evaluated the Navy's proposed 1-fur EEGL of 2,000 ppm for HFC-236fa by considering an acute toxicity study in rats (Keller 1994) and a cardiac sensitization study in dogs (HRC 1994~.
Read the entire page →

Key Terms

  • maternal toxicity
  • cardiac sensitization
  • guidance levels
  • exposure guidance
  • toxicity study

  • toxicity studies
  • developmental toxicity
  • alerting response
  • inhalation studies
  • alerting responses

  • ppm based
  • exposure level
  • subchronic inhalation
  • acute toxicity
  • exposure concentrations

  • reproductive toxicity
  • guidance level
  • peroxisome proliferation
  • subchronic exposure
  • sensitization study

  • rats following
  • exposure concentration
  • submarine exposure
  • day cegl


    • This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
    More information on Chapter Skim is available.