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Submarine Exposure Guidance Levels for Selected Hydrofluorocarbons HFC-236fa, HFC-23,and HFC-404a (2000) / Chapter Skim
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Pages 62-63

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From page 62...
... clinical signs or effects on body weights, food consumption, eye, heart function, respiratory rate, pulse rate, clinical pathology, organ weights, or tissue histopathology. Reproductive and Developmental Toxicity In 1996, the NRC evaluated several inhalation toxicity studies (Hodge et al.
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From page 63...
... . ~ uterine contents ot pregnant he rats sacr't~ceu oetore term were examined, the number of corpora lutea, implants, embryonic deaths, live young, sex ratio, litter weights, and fetal body weights did not differ significantly from controls, and the incidence, type, and distribution of visceral or skeletal abnormalities did not increase.
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Key Terms

  • maternal toxicity
  • male rats
  • clinical signs
  • significant increase
  • clinical pathology

  • inhalation toxicity
  • tissue histopathology
  • pulse rate
  • toxicity studies
  • female rats

  • developmental toxicity
  • rabbits exposed
  • sex ratio
  • fetal body
  • body weights

  • rats exposed
  • weight gains
  • exposed daily
  • pregnant rats
  • uterine contents

  • corpora lutea
  • litter weights
  • significant reductions
  • embryonic deaths
  • organ weights

  • body weight
  • food consumption
  • fetal toxicity
  • survival postpartum
  • slight maternal


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