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Executive Summary
Pages 1-6

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From page 1...
... . The present follow-up report reviews specifically the overall content of the biomedical research programs supported by NASA in order to assess the extent to which current programs are consistent with recommendations of the Strategy report for biomedical research activities.
From page 2...
... Within this context, the committee attempted to answer the following questions. What Is the Balance of Discipline Areas in NASA's Biomedical Research Program?
From page 3...
... However, the Strategy report recommended a major flight component for most discipline research programs, and the current lack of appropriate flight opportunities may lead to delays in the development of needed countermeasures for physiological changes such as orthostatic intolerance and muscle loss. Although it is possible, and even necessary, to perform much of the preliminary work on the ground, many of the critical research questions cannot be resolved without in-flight studies.
From page 4...
... Most of NASA's discipline programs include some level of research activity directed at adverse effects, such as bone and muscle loss, for which no effective countermeasure exists. Studies include investigation of the respective effects of pharmacologic intervention, nutrition, and centrifugation on bone loss, renal stone formation, and sensorimotor impairment.
From page 5...
... Important questions also remain about the availability of Russian cosmonauts for long-term follow-up in the conduct of biomedical research, especially in the early phases of ISS utilization. Countermeasure Testing and Validation The need for effective countermeasures against the deleterious effects of spaceflight on astronaut health and performance will become increasingly critical as longer-duration flights become the norm on the ISS and beyond.
From page 6...
... In particular, NASA should maintain a healthy NRA program as the primary mode for support of spacerelated biomedical research because it remains the best method of accessing the entire investigator community and exploring novel ideas and approaches. REFERENCE National Research Council (NRC)


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