G
CONSENSUS CONCLUSIONS ARRANGED BY HEALTH OUTCOME
Cancer
Sufficient Evidence of a Causal Relationship
-
Benzene and acute leukemia
Sufficient Evidence of an Association
-
Benzene and adult leukemia
-
Solvents and acute leukemia
Limited/Suggestive Evidence of an Association:
-
Tetrachloroethylene and dry-cleaning solvents and bladder cancer
-
Solvents and bladder cancer
-
Tetrachloroethylene and dry-cleaning solvents and kidney cancer
-
Organophosphorous insecticides and non-Hodgkin’s lymphoma
-
Carbamates and non-Hodgkin’s lymphoma
-
Benzene and non-Hodgkin’s lymphoma
-
Solvents and multiple myeloma
-
Organophosphorous insecticides and adult leukemia
-
Solvents and adult leukemia
-
Solvents and myelodysplastic syndromes
Inadequate/Insufficient Evidence to Determine Whether an Association Exists:
-
Solvents and oral, nasal, or laryngeal cancer
-
Insecticides and pancreatic cancer
-
Solvents other than tetrachloroethylene and dry-cleaning solvents and esophageal cancer
-
Solvents and stomach, rectal, or pancreatic cancer
-
Solvents other than trichloroethylene and mixtures of benzene, toluene, and xylene and colon cancer
-
Insecticides and solvents and hepatobiliary cancers
-
Insecticides and lung cancer
-
Solvents other than tetrachloroethylene and dry-cleaning solvents and lung cancer
-
Solvents and bone cancer
-
Solvents and melanoma or nonmelanoma skin cancer
-
Insecticides and soft tissue sarcomas
-
Lindane and solvents and breast cancer
-
Solvents other than trichloroethylene and cervical cancer
-
Solvents and ovarian or uterine cancer
-
Insecticides and prostate, testicular, bladder, or kidney cancers
-
Specific solvents other than tetrachloroethylene and dry-cleaning solvents and bladder cancer
-
Solvents other than tetrachloroethylene and dry-cleaning solvents and kidney cancer
-
Solvents and prostate cancer
-
Insecticides and brain and other central nervous system cancers
-
Specific solvents other than benzene and brain and other central nervous system cancers
-
Specific solvents other than benzene and non-Hodgkin’s lymphoma
-
Insecticides and solvents and Hodgkin’s disease
-
Insecticides and specific solvents and multiple myeloma
-
Specific solvents other than benzene and acute and adult leukemia
-
Benzene and myelodysplastic syndrome
-
Parental preconception exposure to insecticides and childhood leukemias, brain and other central nervous system cancers or non-Hodgkin’s lymphoma
-
Parental preconception exposure to solvents and neuroblastoma or childhood brain cancers
Limited/Suggestive Evidence of NO Association
-
No findings
Neurologic Effects
Sufficient Evidence of a Causal Relationship
-
No findings
Sufficient Evidence of an Association
-
No findings
Limited/Suggestive Evidence of an Association:
-
Organophosphorous insecticide exposure with OP poisoning and long-term neurobehavioral effects (that is, abnormal results on neurobehavioral test batteries and symptom findings)
-
Solvents and neurobehavioral effects (that is, abnormal results on neurobehavioral test batteries and symptom findings)
Inadequate/Insufficient Evidence to Determine Whether an Association Exists:
-
Insecticides and solvents and peripheral neuropathy
-
Insecticides and solvents and Parkinson’s Disease
-
Insecticides and solvents and amyotrophic lateral sclerosis
-
Insecticides and solvents and Alzheimer’s Disease
-
Solvents and multiple sclerosis
-
Solvents and a long-term reduction in color discrimination
-
Solvents and long-term hearing loss
-
Solvents and long-term reduction in olfactory function
Limited/Suggestive Evidence of NO Association
-
No findings
Reproductive Effects
Sufficient Evidence of a Causal Relationship
-
No findings
Sufficient Evidence of an Association
-
No findings
Limited/Suggestive Evidence of an Association:
-
No findings
Inadequate/Insufficient Evidence to Determine Whether an Association Exists:
-
Insecticides and solvents and male or female infertility after cessation of the exposure
-
Parental preconception exposure to insecticides or solvents and spontaneous abortion or other adverse pregnancy outcomes
-
Parental preconception exposure to insecticides or solvents and congenital malformations
Limited/Suggestive Evidence of NO Association
-
No findings
Other Health Effects
Sufficient Evidence of a Causal Relationship
-
Benzene and aplastic anemia
Sufficient Evidence of an Association
-
Propylene glycol and allergic contact dermatitis
Limited/Suggestive Evidence of an Association:
-
Solvents and reactive airways dysfunction syndrome (RADS) which would be evident with exposure and could persist for months or years
-
Solvents and hepatic steatosis
-
Solvents and chronic glomerulonephritis
-
Insecticides and allergic contact dermatitis
Inadequate/Insufficient to Determine Whether an Association Exists:
-
Insecticides and aplastic anemia
-
Solvents other than benzene and aplastic anemia
-
Insecticides and solvents and irreversible cardiovascular outcomes
-
Insecticides and solvents and persistent respiratory symptoms or impairment after cessation of exposure
-
Solvents and alterations in liver function tests after cessation of exposure
-
Solvents and cirrhosis
-
Solvents and chronic pancreatitis or other persistent gastrointestinal outcomes
-
Solvents and the systemic rheumatic diseases: scleroderma, rheumatoid arthritis, undifferentiated connective tissue disorders, and systemic lupus erythematosus
Limited/Suggestive Evidence of NO Association
-
No finding